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Central Auditory Processing in Children is Affected by Perinatal HIV Exposure.
Pediatr Infect Dis J
March 2025
Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.
Background: Children living with HIV are at higher risk for hearing loss compared to children with HIV-unexposed, uninfected (HUU). There is little known regarding the effects of children living with perinatally-acquired HIV (PHIV) and those living with perinatal HIV exposure but uninfected (PHEU) on central auditory function.
Methods: Children aged 11-14 years who were participating in the Auditory Research in Children with HIV study.
The causal effects of inflammatory bowel disease on its ocular manifestations: A Mendelian randomization study.
PLoS One
March 2025
Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Background: Observational studies have shown that ocular manifestations of inflammatory bowel disease (IBD) are common extraintinal manifestations, among which iridocyclitis, scleritis and episcleritis are the most common. However, whether there is a causal relationship between the two is unclear. The purpose of this study was to evaluate the causality of IBD on ocular manifestations using the mendelian randomization (MR) analysis.
View Article and Find Full Text PDFStable isotopes as a predictor for organic or conventional classification of berries and vegetables.
PLoS One
March 2025
Department of Land, Air and Water Resources, University of California-Davis, Davis, California, United States of America.
Organic agriculture is expanding worldwide, driven by expectations of improving food quality and soil health. However, while organic certification by regulatory bodies such as the United States Department of Agriculture and the European Union confirms compliance with organic standards that prohibit synthetic chemical inputs, there is limited oversight to verify that organic practices, such as the use of authentic organic fertilizer sources, are consistently applied at the field level. This study investigated the elemental content of carbon (C) and nitrogen (N) and their stable isotopes (δ13C and δ15N) in seven different crops grown under organic or conventional practices to assess their applicability as a screening tool to verify the authenticity of organic labeled produce.
View Article and Find Full Text PDFEfficacy and safety of mesenchymal stem cell therapies in retinitis pigmentosa: a systematic review and meta-analysis.
Int Ophthalmol
March 2025
Burapha University Hospital, Burapha University, Saen Suk, Chonburi, Thailand.
Background: Retinitis pigmentosa (RP) is a retinal dystrophy and genetically heterogeneous group that causes vision loss and necessitates innovative therapeutic strategies, and mesenchymal stem cell (MSC) therapy has shown potential due to its regenerative and immunomodulatory properties. This meta-analysis aims to evaluate the efficacy and safety of MSC therapies in improving visual outcomes, focusing on the impact of various MSC types, administration methods, and duration of benefits.
Methods: A systematic search of peer-reviewed studies was conducted to identify clinical trials and observational studies investigating MSC therapies for retinal conditions.
The causal relationships between inflammatory cytokines, blood metabolites, and thyroid cancer: a two-step Mendelian randomization analysis.
Discov Oncol
March 2025
Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Background: Thyroid cancer is a prevalent malignant tumor, especially with a higher incidence in women. Tumor microenvironment changes induced by inflammation and alterations in metabolic characteristics are critical in the development of thyroid cancer. Nevertheless, their causal relationships remain unclear.
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