Infective endocarditis remains a deadly disease with a significant mortality rate. While ventricular septal defects (VSDs) have been linked to an increased risk of infective endocarditis, cases of acquired VSDs resulting from infective endocarditis are not well-documented in the literature. Our report highlights a rare case of acquired VSD that resulted directly from aortic valve endocarditis, treated with successful repair and placement of permanent pacemaker.
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http://dx.doi.org/10.1186/s13019-024-03244-2 | DOI Listing |
Infez Med
March 2025
Department of Microbiology, All India Institute of Medical Sciences, Kalyani, India.
We report a rare clinical presentation of a 54-year-old male diagnosed with infective endocarditis caused by , a nutritionally variant streptococcus (NVS) characterized by unique growth requirements and high pathogenic potential. The patient presented with prolonged fever and residual hemiparesis following an ischemic stroke. Blood culture confirmed , and imaging identified vegetations on a bicuspid aortic valve.
View Article and Find Full Text PDFCureus
February 2025
Department of General Medicine, Saga University Hospital, Saga, JPN.
Infective endocarditis (IE) often presents as a fever of unknown origin due to its extremely diverse clinical presentations, requiring diverse advanced medical equipment and tests to make a correct diagnosis. Whether a physician can suspect IE in a clinical setting is dependent on the physician's knowledge and experience. If IE is not suspected, antibiotics are administered without obtaining blood cultures, complicating the clinical course and prognosis.
View Article and Find Full Text PDFJ Cardiothorac Surg
March 2025
University of North Dakota School of Medicine and Health Sciences, 1301 N Columbia Rd Stop 9037, Grand Forks, ND, 58202-9037, USA.
Infective endocarditis remains a deadly disease with a significant mortality rate. While ventricular septal defects (VSDs) have been linked to an increased risk of infective endocarditis, cases of acquired VSDs resulting from infective endocarditis are not well-documented in the literature. Our report highlights a rare case of acquired VSD that resulted directly from aortic valve endocarditis, treated with successful repair and placement of permanent pacemaker.
View Article and Find Full Text PDFStroke related to infections represents a less common but significant cause, particularly in low- and middle-income countries. This review examines the pathophysiology of stroke from infections, involving both direct and indirect mechanisms. Bacterial infections such as tuberculous meningitis and infective endocarditis can directly cause strokes through local inflammation, arteritis, and septic embolism.
View Article and Find Full Text PDFRev Esp Geriatr Gerontol
March 2025
Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, España; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España; Servicio de Microbiología y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, España.
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