Background: Transphyseal hematogenous osteomyelitis(THO) has been considered a potential cause of severe sequelae due to its damage to the growth plate. It has been reported that growth disturbance would take place if the area of involvement exceeds 7%. However, the growth plate seems to have more potential to recover and regain normal function.
Case Presentation: We report three cases of hematogenous osteomyelitis(HO) in children (ages 9 weeks, 4 years, and 13 years respectively ) with significant physeal involvement. All patients underwent surgical debridement and antibiotic therapy. Follow-up assessments demonstrated full recovery, with normal knee movements, no pain and equal limb length. Complete recovery of the physeal plate morphology and normal subsequent development were observed.
Conclusions: THO in children may have the chance of complete recovery after proper treatment, suggesting that the physeal plate has a great potential for self-recovery.
Clinical Trial Number: Not applicable.
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http://dx.doi.org/10.1186/s12891-025-08475-5 | DOI Listing |
BMC Musculoskelet Disord
March 2025
Department of Pediatric Orthopedics, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Background: Transphyseal hematogenous osteomyelitis(THO) has been considered a potential cause of severe sequelae due to its damage to the growth plate. It has been reported that growth disturbance would take place if the area of involvement exceeds 7%. However, the growth plate seems to have more potential to recover and regain normal function.
View Article and Find Full Text PDFJ Bone Joint Surg Am
December 2024
Pediatric Orthopaedic Unit, Pediatric Surgery Service, Geneva University Hospitals, Geneva, Switzerland.
Background: Transphyseal hematogenous osteomyelitis (THO) is a common infectious condition, being present in 25% of patients with hematogenous osteomyelitis. A large proportion of pediatric hematogenous osteomyelitis infections can spread through the growth cartilage and therefore may be potentially responsible for growth disorders, leading to limb-length discrepancy or angular deformities. The purpose of the present study was to identify both the prevalence of complications caused by transphyseal osteomyelitis and factors influencing their occurrence.
View Article and Find Full Text PDFMicroorganisms
March 2023
Pediatric Orthopedics Unit, Pediatric Surgery Service, Geneva University Hospitals, CH-1211 Geneva, Switzerland.
Transphyseal hematogenous osteomyelitis (THO) is a serious condition that can affect the growing physis, yet it is insufficiently recognized in children. The aim of this study was to explore the prevalence and epidemiology of pediatric THO, and to discuss the underlying pathophysiology. All consecutive cases of acute and subacute osteomyelitis admitted to our institution over 17 years were retrospectively studied.
View Article and Find Full Text PDFBMC Med Imaging
May 2015
Unit of Pediatric Orthopedics, University Hospital, Geneva, Switzerland.
Background: In children, septic arthritis (SA) of the hip is either primary or concomitant with acute haematogenous osteomyelitis (AHO). However, seldom, patients with isolated SA at presentation, may later show osteomyelitis in the metaphysis. The aim of this study was to elaborate a physiopathological hypothesis based on the peculiar MRI findings to explain the onset of AHO after SA.
View Article and Find Full Text PDFAJR Am J Roentgenol
July 2014
1 Department of Medical Imaging, University of Arizona, 1501 N Campbell Ave, PO Box 245067, Tucson, AZ 85724-5067.
Objective: Radiologists are taught that pyogenic osteomyelitis in children rarely crosses the growth plate because terminal vessels of nutrient arteries loop at the physis, predisposing the metaphysis to hematogenous infection. However, we note that MRI frequently shows osteomyelitis involving both sides of the physis. The purpose of this article is to document our observation that pyogenic osteomyelitis crosses the growth plate more frequently in the pediatric patient population than is classically taught.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!