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Immunity and neuroinflammation in early stages of life and epilepsy.
Epilepsia
March 2025
Departamento de Neurologia e Neurocirurgia, Escola Paulista de Medicina, Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil.
The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy. Both central and even peripheral inflammation may impact brain function, promoting opening of the blood-brain/blood and cerebrospinal barriers and allowing entry of immune cells and cytokines, which in turn may affect neuron function and connections.
View Article and Find Full Text PDFCorrection: Barriers and facilitators of transition of adolescents living with HIV into adult care in under-resourced settings of Southern Ethiopia: a qualitative study.
BMC Public Health
March 2025
School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Zoom-Delivered Empowered Relief for Chronic Pain: Observational Longitudinal Pilot Study Exploring Feasibility and Pain-Related Outcomes in Patients on Long-Term Opioids.
JMIR Form Res
March 2025
Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, United States.
Background: Patients with chronic pain on long-term opioid therapy often face barriers to accessing effective nonpharmacological treatments, including the burden of multiple sessions, lack of trained clinicians, and travel time. Empowered Relief (ER), a 2-hour, single-session pain relief skills class, can improve pain and quality of life among patients with chronic pain when delivered in person or virtually.
Objective: This study examined the impact of Zoom-delivered ER among people with chronic pain on long-term opioid therapy.
Shaping cancer center priorities through Community Advisory Board collaboration.
Res Involv Engagem
March 2025
University of Iowa College of Public Health, 145 N. Riverside Dr, Iowa City, IA, 52242, USA.
Background: Community Outreach and Engagement (COE) teams at National Cancer Institute-designated comprehensive cancer centers are tasked with engaging communities to understand and address the burden of cancer within their catchment area. This helps cancer center leadership identify priorities and develop strategic plans to reduce the cancer burden. University of Iowa Health Care Holden Comprehensive Cancer Center collaborates with its Community Advisory Board (CAB) to understand the needs and priorities of its catchment area, the state of Iowa.
View Article and Find Full Text PDFFlowCron - Increasing access to HPC by wrapping Globus into a function-as-a-service.
Wellcome Open Res
January 2025
The Rosalind Franklin Institute, Rutherford Appleton Laboratory, Harwell Campus, Didcot, England, OX11 0FA, UK.
Despite significant investment in High-Performance Computing (HPC) clusters by funding councils, there are still many researchers whose workflows could not benefit from the computation speed that is provided by these clusters. Reducing barriers to entry for these researchers would accelerate their scientific throughput, since they will be able to respond to results in a timely fashion, improving either their protocols or correcting any problems that might have arisen. This improves the quality of science, and therefore the return on investment, in computationally-intensive areas such as Cryogenic Electron Microscopy (cryo-EM).
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