Background: The management of patients with concomitant gallbladder stones with silent CBDS still involves a wide range of debates, and there is little evidence regarding the recommendation of CBD clearance either before cholecystectomy or in the same session. In this study, we aimed to discuss the feasibility of performing LC with a wait-and-see strategy for patients with silent CBS.
Method: Patients with silent CBDS identified during preoperative examinations for gallbladder stones were studied for the feasibility of performing LC with a wait-and-see strategy for silent CBS.
Results: Sixty patients who presented with gallbladder stones with silent CBDS underwent LC between February 2023 and July 2023. Seventeen patients (28.3%) underwent laparoscopic acute cholecystectomy, and 43 (71.7%) patients underwent laparoscopic elective cholecystectomy; all of these procedures were completed laparoscopically. Two patients (3.3%) developed symptomatic CBDS, both of whom were treated medically without intervention. Sixteen patients (26.7%) experienced spontaneous CBDS during the follow-up period.
Conclusion: Patients who present with symptomatic gall bladder stones either acutely or electively with asymptomatic CBDS can undergo laparoscopic cholecystectomy without suffering from CBDS with acceptable short-term outcomes.
Trial Registration: This study was registered at Suez med - IRB office under trial registration no. 6 and registered at clinicaltrials.gov (NCT06349876) in 31/3/2024.
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http://dx.doi.org/10.1186/s12876-024-03459-6 | DOI Listing |
Actas Esp Psiquiatr
March 2025
Graduate School, Harbin Sport University, 150008 Harbin, Heilongjiang, China; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, 150000 Harbin, Heilongjiang, China.
Background: Neuroinflammation and neurogenic disorders lead to depression in stroke patients. As, exercise intervention, a non-drug therapy, has been proven effective in post-stroke depression (PSD) patients. However, the underlying molecular mechanism by which exercise improves PSD still needs to be explored.
View Article and Find Full Text PDFBMC Gastroenterol
March 2025
Department of General Surgery, Qena Faculty of Medicine, South Valley University, Qena city, Egypt.
Background: The management of patients with concomitant gallbladder stones with silent CBDS still involves a wide range of debates, and there is little evidence regarding the recommendation of CBD clearance either before cholecystectomy or in the same session. In this study, we aimed to discuss the feasibility of performing LC with a wait-and-see strategy for patients with silent CBS.
Method: Patients with silent CBDS identified during preoperative examinations for gallbladder stones were studied for the feasibility of performing LC with a wait-and-see strategy for silent CBS.
Introduction: Human Endogenous RetroViruses (HERVs) account for approximately 8% of the human genome, where they are integrated and typically remain silent. Despite their inactivation, numerous retroviral sequences retain intact open reading frames (ORFs) capable of producing retroviral transcripts and/or proteins, which have been detected in colon cancer.
Methods: Three different cohorts of patients who underwent surgery at three different hospitals, comprising 167 Italian and Tunisian colon cancer patients, were analyzed.
Am J Physiol Heart Circ Physiol
March 2025
Department of Biochemistry, AIIMS Raipur, Raipur, Chhattisgarh, India.
In individuals with diabetic hypertension, silent coronary artery disease (CAD) is common due to underlying chronic inflammation but there is no biomarker to monitor this high-risk group of individuals before noticeable symptoms emerge clinically. cfDNA from dying endothelial cells triggers chronic inflammation, leading us to hypothesize that enzymes that degrade cfDNA, DNase I and/or II, could serve as more sensitive biomarkers for silent CAD. To test this, we conducted a study with 30 hypertensive diabetic patients with clinical symptoms of CAD (CAD-HTN-DM) and 30 controls without CAD (HTN-DM).
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
January 2025
Sinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Rhinoplasty is the most common cosmetic surgery procedure in Iran. One of the complications of this procedure that has been less considered is the probable effect of rhinoplasty on voice. This study aimed to assess the influence of rhinoplasty on acoustic characteristics of resonance and sound production.
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