Purpose: Anterior knee pain is a frequent symptom caused by disorders like patellofemoral pain syndrome or patella tendon tendinitis, which is commonly treated conservatively. The aim of the current study was to examine the effectiveness of a digital therapeutic (DT) versus German standard care through a prospective, randomized, multicenter controlled trial.

Methods: Study participants were recruited in 9 orthopedic specialist centers diagnosed with anterior knee pain and a NPRS score of ≥ 4. Stratified randomization for n = 140 participants was conducted, assigning participants to the intervention group (exclusive use of DT) or the control group (standard care). Standard care included 1-3 prescriptions for physical therapy, while the DT consisted of a 90-day personalized exercise therapy program including educational content. The primary endpoints were pain measured by NPRS and functional impairment measured by the Kujala Score.

Results: The use of the DT compared to the standard care showed an improvement in clinical outcomes (NPRS = - 3.7 ± 2.67 and Kujala = 18.00 ± 13.96, both p < 0.001). Both pain and function improved clinically and statistically significantly compared to the control group (ANOVA: NPRS = - 1.64 ± 0.35, p < 0.001, Kujala = 9.26 ± 2.52, p < 0.01).

Conclusion: The use of the DT showed significant improvements in pain and function compared to the current standard therapy. These results are highly relevant for clinical practice in the treatment decision-making for patients with anterior knee pain as the DT bridges effectively gaps in the healthcare systems.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00402-025-05787-yDOI Listing

Publication Analysis

Top Keywords

standard care
20
anterior knee
12
digital therapeutic
8
compared standard
8
knee pain
8
standard
5
care
5
application digital
4
therapeutic reveals
4
reveals superior
4

Similar Publications

Background: Processing data from electronic health records (EHRs) to build research-grade databases is a lengthy and expensive process. Modern arthroplasty practice commonly uses multiple sites of care, including clinics and ambulatory care centers. However, most private data systems prevent obtaining usable insights for clinical practice.

View Article and Find Full Text PDF

Background: Breast cancer is the second most common cancer in women worldwide. Treatments for this disease often result in side effects such as pain, fatigue, loss of muscle mass, and reduced quality of life. Physical exercise has been shown to effectively mitigate these side effects and improve the quality of life in patients with breast cancer.

View Article and Find Full Text PDF

Background: Critically ill children are at risk for subtherapeutic antibiotic concentrations. The frequency of target attainment and risk factors for subtherapeutic concentrations of cefepime in children have not been extensively studied.

Methods: We performed an observational study in critically ill children receiving a new prescription of standard dosing of cefepime for suspected sepsis (≥2 systemic inflammatory response syndrome criteria within 48 hours of cefepime start).

View Article and Find Full Text PDF

This consensus position statement of the American Academy of Neurology, American Epilepsy Society, and Epilepsy Foundation of America updates prior 1994 and 2007 position statements on seizures, driver licensure, and medical reporting. Key consensus positions include the following: (1) in the United States, national driving standards promulgated through a system such as the Uniform Law Commission would reduce confusion and improve adherence with state driving standards; (2) state licensing criteria for medical conditions should be promulgated by regulations and guidelines based on enabling legislation rather than in statutes themselves and should be developed by medical advisory boards working in collaboration with departments of motor vehicles; (3) licensing criteria should be equitable, nondiscriminatory, objective, and compatible with comparable risks in other populations; (4) a minimum seizure-free interval of 3 months should ordinarily be required before driving in all cases and should be extended in individual cases based on review of favorable and unfavorable features by medical advisory boards; (5) individuals with exclusively provoked seizures attributable to provoking factors that are unlikely to reoccur in the future may not require a seizure-free interval before resuming driving; (6) individuals with previously well-controlled epilepsy who experience seizures due to short-term interruptions of antiseizure medications in the setting of hospitalization or practitioner-directed medication-titration may not require a seizure-free interval before driving once previously effective levels of antiseizure medications have been resumed; (7) patients and practitioners should pause driving during tapering and following discontinuation of an antiseizure medication if another such medication is not introduced; (8) individuals whose cognition or coordination is impaired due to medications used to prevent seizures should refrain from driving; (9) health care practitioners should be allowed but not mandated to report drivers who pose an elevated risk; but (10) neither a decision to report a patient suspected of being at elevated risk nor a decision declining to report a patient suspected of being at elevated risk should be subject to legal liability; (11) nations, states, and municipalities should provide alternative methods of transportation and accommodations for individuals whose driving privileges are restricted due to medical conditions.

View Article and Find Full Text PDF

Background: In Germany, the incidence of traumatic spinal cord injury is approximately 16 per million inhabitants per year. This article aims to present evidence-based diagnostic and therapeutic measures for the first 14 days after injury to minimize neural damage, prevent complications, and preserve functioning as much as possible.

Methods: After the formulation of key questions, systematic literature searches were carried out on multiple topics.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!