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In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity.
J Immunol
March 2025
Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Leukocytes migrate through the blood and extravasate into organs to surveil the host for infection or cancer. Recently, we demonstrated that intravenous (IV) anti-CD45.2 antibody labeling allowed for precise tracking of leukocyte migration.
View Article and Find Full Text PDFLong-term impact of bevacizumab for the treatment of brain radiation necrosis.
J Neurooncol
March 2025
Neuro-Oncology Unit, Davidoff Cancer Center, Rabin Medical Center- Beilinson Hospital, Petach Tikva, Israel.
Purpose: To evaluate short and long-term efficacy of bevacizumab (Bev), for the treatment of radiation necrosis (RN) in patients with brain metastasis after stereotactic radiosurgery (SRS).
Methods: The database of a tertiary medical center was reviewed for all adult patients treated by Bev (from January 2018 to January 2023) for RN after having received SRS for BM. Clinical and MRI data were systematically collected at baseline, immediately after the completion of Bev treatment, and at 6, 12, and, when available, 24 months post-treatment.
Low-Cost, Facile, and Scalable Manufacturing of Single-Molecule-Integrated Catalytic Electrodes.
ACS Nano
March 2025
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China.
To surmount the shortcomings of powder-based catalysts and small electrode sizes, the development of meter-scale integrated electrode materials is essential for practical electrocatalytic applications, which requires fine control over the effective surface grafting of catalytic active sites on large-size electrodes as well as addressing the challenge of balancing cost-effective and large-scale manufacturing with highly active and stable operation. Herein, we report a low-cost, facile, and scalable method for directly constructing meter-scale single-molecule-integrated catalytic electrodes using commercially available, flexible, and size-tailored conductive carbon textiles (e.g.
View Article and Find Full Text PDFProtothecosis in Dogs: A Narrative Review.
J Vet Intern Med
March 2025
Centre for Veterinary Education, Sydney School of Veterinary Science, The University of Sydney, Sydney, Australia.
Protothecosis is a rare and unusual disease that affects both humans and animals, including dogs. The causative agents are unicellular, achlorophyllous, "yeast-like" microalgae of the genus Prototheca (Trebouxiophyceae, Chlorophyta). Although usually saprophytic, Prototheca may, under conditions of immunologic compromise, become pathogenic and even lethal to the host.
View Article and Find Full Text PDFThis paper systematically reviews literature to date about how child welfare workers' decisions about neglect are influenced by their environments. We conducted a systematic search of Web of Science, Embase, PsycInfo, Scopus, and Applied Social Sciences Index & Abstracts, looking for studies in English of any methodology, published since the 1989 Children Act, in which statutory thresholds in England are defined. We used child welfare workers' definitions of neglect or, in the absence of this, defined "neglect" as harmful acts of omission by a caregiver (failure to do something necessary for a child's well-being).
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