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The XI International Symposium on Fish Parasites: fish health, parasite biodiversity, and conservation.
Trends Parasitol
March 2025
Escuela Nacional de Estudios Superiores Unidad Mérida (ENES-Mérida), Universidad Nacional Autónoma de México, Mérida, Yucatán, Mexico.
Raising the bar in respiratory care by EUFOREA: report of the European Union Parliament Symposium, April 2024.
Front Allergy
February 2025
Department of Allergy & Rhinology, Royal National ENT Hospital, London, United Kingdom.
Article Synopsis
- In April 2024, the European Summit on chronic respiratory diseases (CRDs) was held in the European Parliament, organized by EUFOREA and hosted by MEPs Dorien Rookmaker and Mislav Kolakušić.
- The Summit aimed to address the challenges faced by European patients with CRDs by fostering collaboration among various European and global health organizations.
- Representatives from multiple societies and patient associations discussed strategies to improve respiratory care and prevention by sharing their visions and action plans.
Efficacy of Navigation Systems With Smart Delivery Tools in Enhancing the Accuracy of Percutaneous Pedicle Screw Insertion.
Cureus
February 2025
Department of Spine Surgery, Tokyo Spine Clinic, Tokyo, JPN.
Purpose Minimally invasive surgical techniques are advancing in spinal surgery, creating a need for the development of surgical support systems. This study evaluates the efficacy of a compact navigation system with smart delivery tools in percutaneous pedicle screw insertion. Methods This retrospective observational study included consecutive thoracic or lumbar spinal fusion patients with percutaneous pedicle screw placement treated from November 2022 to July 2023 in a Japanese private hospital.
View Article and Find Full Text PDFHereditary Angioedema with Normal C1 Inhibitor: an Updated International Consensus Paper on Diagnosis, Pathophysiology, and Treatment.
Clin Rev Allergy Immunol
March 2025
Angioedema Center of Reference and Excellence (ACARE), Institute of Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
Hereditary angioedema (HAE) has been recognized for almost 150 years. The newest form of HAE, where C1 inhibitor levels are normal (HAE-nC1INH), was first described in 2000. Over the last two decades, new types of apparent non-mast cell-mediated angioedema with normal quantity and activity of C1INH have been described, in some cases with proven genetic pathogenic variants that co-segregate with angioedema expression within families.
View Article and Find Full Text PDFEvaluation of Innate Immune System, Body Habitus, and Sex on the Pharmacokinetics and Pharmacodynamics of Anetumab Ravtansine in Patients With Cancer.
Clin Transl Sci
March 2025
UNC Eshelman School of Pharmacy, UNC Lineberger Comprehensive Cancer Center, and UNC Advanced Translational Pharmacology and Analytical Chemistry Lab at University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Anetumab ravtansine, like other ADC drugs, has high inter-patient variability in its pharmacokinetic (PK) and pharmacodynamic (PD) outcomes, which raises concerns about whether current dosing regimens are optimal for patients. The objective of this study was to evaluate covariates, especially body habitus and the innate immune system (IIS), which may affect anetumab ravtansine PK and PD as part of two clinical trials in patients with ovarian cancer and mesothelioma. Biomarkers of Fcγ receptors(FcγR) CD64 on IIS cells, total body weight (TBW), body surface area (BSA), and other covariates, such as sex and age, were analyzed for an association with anetumab ravtansine PK.
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