Abdominal Wall Reinforcement Using OviTex after Deep Inferior Epigastric Perforator Flap.

Background Abdominal wall bulges and hernias are not uncommon complications following deep inferior epigastric perforator (DIEP) flap harvest. Abdominal wall reinforcement using synthetic meshes has been found to decrease bulges by up to 70%; however, such meshes can be associated with other issues such as seromas and infections. Reinforced tissue matrix (RTM) mesh can be used for abdominal wall reinforcement due to its ability to recruit fibroblasts and provide a scaffold for cellular proliferation. There is no literature on the use of OviTex mesh for abdominal wall reinforcement following DIEP flap harvest. Therefore, this study aimed to evaluate the efficacy and safety of its use in this setting. Methods A retrospective review was performed on patients undergoing DIEP flap harvest between 01/2020-06/2023. Patients who had completed at least 12 months of follow-up visits were included. Descriptive, univariate, and multiple logistic regression analysis were completed. Results A total of 199 patients were included. The mean age at the time of surgery was 51.1±10.0 years and the mean body mass index was 30.2±5.9 kg/m2. Abdominal wall reinforcement was completed in 85 (42.7%) patients. Patients that had OviTex placed developed fewer bulges compared to the non-mesh cohort(0% vs 5.3%, P=0.04). Furthermore, OviTex mesh did not increase adverse events and was not significantly different in seroma/hematoma rates when compared to the non-mesh cohort (10.6% vs 5.3%, P=0.26). Conclusion This study demonstrates that OviTex mesh is safe and efficacious in reducing the rate of bulges following DIEP flap harvest without increasing other complications.