Motor coordination relies on muscle spindles and the stretch reflexes they enable. A new study shows that spindle-resident macrophages can drive sensory signaling and muscle contraction. This implicates immune cells in a process considered the exclusive domain of neuromuscular systems.
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http://dx.doi.org/10.1016/j.cub.2025.01.040 | DOI Listing |
Handb Clin Neurol
March 2025
School of Kinesiology, Louisiana State University, Baton Rouge, LA, United States.
Using a historical or "development from" approach to study the development of hand-use preferences in infants and children, we show how various sensorimotor experiential events shape the cascade from initial to subsequent hand-use preferences. That cascade represents, creates, and shapes the lateralized asymmetry of neural circuits in the cerebral hemispheres. The control of the preferred hand requires neural circuits in the contralateral hemisphere that are capable of processing the organization of finely timed, sequentially organized movements and detecting haptic information derived from high-frequency transitions in the stimulus.
View Article and Find Full Text PDFClin Neurophysiol
March 2025
Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Objective: To analyze exercise-induced changes in functional connectivity (FC) using high-density EEG (HD-EEG) and primary motor cortex excitability via paired-pulse TMS (pp-TMS).
Methods: Ten healthy volunteers performed a 3 km high-intensity run. Neurophysiological assessments were conducted at baseline (T0), 24 h (T1), and 72 h (T2) post-exercise.
Integr Psychol Behav Sci
March 2025
Department of Educational Psychology, University of Education Weingarten, Weingarten, Germany.
In this paper, we discuss symbolic, situational, and verbal mathematical processing. These three modes of processing are conducted by the mediums of symbolic, situational, and verbal mathematical representations. While symbolic processing is a suppressive-oriented mechanism, situational one is receptive-oriented and reliant on sensorimotor features of elements in the context of mathematical representation.
View Article and Find Full Text PDFGenes Brain Behav
April 2025
Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
The fundamental skills for motor coordination and motor control emerge through development. Neurodevelopmental disorders such as developmental coordination disorder (DCD) lead to impaired acquisition of motor skills. This study investigated motor behaviors that reflect the core symptoms of human DCD through the use of BXD recombinant inbred strains of mice that are known to have divergent phenotypes in many behavioral traits, including motor activity.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Psychology, The American College of Greece, Athens, Greece.
The high levels of polarization raise concerns about individuals' decreased ability to empathize and understand the representatives of political out-groups. As such, our political biases may lead us to misunderstand out-group politicians. In the current study, we examine the mu rhythm, a neural oscillation in the sensorimotor cortex related to the processing and understanding of other people's actions, intentions and emotions.
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