Sensorimotor function: Muscle spindle macrophages in the loop.

Curr Biol

Department of Medical and Translational Biology, Umeå University, 901 87 Umeå, Sweden. Electronic address:

Published: March 2025

Motor coordination relies on muscle spindles and the stretch reflexes they enable. A new study shows that spindle-resident macrophages can drive sensory signaling and muscle contraction. This implicates immune cells in a process considered the exclusive domain of neuromuscular systems.

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http://dx.doi.org/10.1016/j.cub.2025.01.040DOI Listing

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