While the ability of an animal to rapidly learn to detect and avoid threats is critical for survival, previous research has focused on post-learning time periods. A new computational study now reveals how prefrontal cortex neural population dynamics underlie rapid threat avoidance learning.
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http://dx.doi.org/10.1016/j.cub.2025.01.039 | DOI Listing |
Background: Medication misuse is a threat to public health and patient safety, and strategies to prevent medication misuse should be incorporated in nursing education.
Method: An interdisciplinary nursing and pharmacy team collaborated on a pilot project with graduate FNP students to adapt and evaluate a training program for pharmacy students on the prevention of medication misuse for nursing based on the publicly available online program Generation Rx.
Results: Of 39 students who participated in the training, 74% ( = 29) completed pre- and posttest surveys.
Front Oncol
February 2025
Department of General Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, China.
Colorectal cancer (CRC) is a prevalent malignant tumor in the digestive system. As reported in the 2020 global cancer statistics, CRC accounted for more than 1.9 million new cases and 935,000 deaths, making it the third most common cancer worldwide in terms of incidence and the second leading cause of cancer-related deaths globally.
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February 2025
Department of Urology, Institute of Urology, Gansu Province Clinical Research Center for Urinary System Disease, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Objective: Prostate cancer is a major threat to global male health. This study uses bibliometric methods to analyze the dynamics and trends in prostate cancer screening research, with the aim of optimizing screening strategies and informing policy decisions.
Methods: Utilizing the Web of Science Core Collection database, this study retrieved prostate cancer screening-related literature published between 2014 and 2024, totaling 5,409 articles.
Front Immunol
March 2025
Department of Gynecology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Background: Ovarian cancer (OC) is a severe malignant tumor with a significant threat to women's health, characterized by a high mortality rate and poor prognosis despite conventional treatments such as cytoreductive surgery and platinum-based chemotherapy. Cuproptosis, a novel form of cell death triggered by copper ion accumulation, has shown potential in cancer therapy, particularly through the involvement of CuLncs. This study aims to identify risk signatures associated with CuLncs in OC, construct a prognostic model, and explore potential therapeutic drugs and the impact of CuLncs on OC cell behavior.
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February 2025
Department of Computer Science & Engineering, Indian Institute of Technology Ropar, Rupnagar, India.
Machine learning techniques have emerged as a promising tool for efficient cache management, helping optimize cache performance and fortify against security threats. The range of machine learning is vast, from reinforcement learning-based cache replacement policies to Long Short-Term Memory (LSTM) models predicting content characteristics for caching decisions. Diverse techniques such as imitation learning, reinforcement learning, and neural networks are extensively useful in cache-based attack detection, dynamic cache management, and content caching in edge networks.
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