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Reclassification of Airflow Limitation: A STAR with a GOLD Lining.
Am J Respir Crit Care Med
March 2025
Pulmonary Medicine, Internal Medicine, KARLSKRONA, Blekinge, Sweden.
Impact of reduced forced expiratory volume on cardiac prognosis in patients with chronic heart failure.
Heart Vessels
September 2018
Department of Pulmonary Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
In patients with chronic heart failure (CHF), comorbidity of airflow limitation is associated with poor outcomes. The forced expiratory volume in 1 s (FEV) is used to evaluate the severity of airflow limitation. However, the impact of FEV severity on prognosis has only been partially elucidated in patients with CHF.
View Article and Find Full Text PDFSpirometric Criteria for Chronic Obstructive Pulmonary Disease in Clinical Trials of Pharmacotherapy.
COPD
February 2018
b Department of Internal Medicine , Yale University School of Medicine, New Haven , Connecticut , USA.
Clinical trials of pharmacotherapy in chronic obstructive pulmonary disease (COPD) often include older persons with moderate-to-severe airflow-obstruction, as defined by the Global Initiative for chronic Obstructive Lung Disease (GOLD). In this context, spirometric airflow-obstruction establishes COPD. Because GOLD misidentifies COPD and its severity in older persons, we set out to apply more age-appropriate spirometric criteria from the Global Lung function Initiative (GLI) in a prior clinical trial of COPD pharmacotherapy, specifically the Towards a Revolution in COPD Health (TORCH) trial - N = 6,112, mean age 65 years.
View Article and Find Full Text PDFCommonly Used Patient-Reported Outcomes Do Not Improve Prediction of COPD Exacerbations: A Multicenter 4½ Year Prospective Cohort Study.
Chest
December 2017
Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Background: Several cross-sectional and short-term studies suggest that patient-reported outcomes (PROs) may be useful to help predict COPD exacerbations, but evidence from long-term prospective cohort studies is lacking. Our aim was to assess if PROs add to the prediction of exacerbations.
Methods: Four hundred eight primary care patients with COPD participated in the multicenter prospective International Collaborative Effort on Chronic Obstructive Lung Disease: Exacerbation Risk Index Cohorts (ICE COLD ERIC) study.
Comparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study.
Int J Chron Obstruct Pulmon Dis
August 2017
Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima.
Background: The incidence of chronic obstructive pulmonary disease (COPD) is increasing worldwide. In Japan and other countries, epidemiological studies have found that many patients with COPD are underdiagnosed and untreated, and thus, early detection and treatment of COPD has been emphasized. Screening questionnaires may have utility in the initial detection of COPD.
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