Hydrogen detection plays a crucial role in various scenes of hydrogen energy such as hydrogen vehicles, hydrogen transportation and hydrogen storage. It is essential to develop a hydrogen detection system with ultrafast response times (<1 s) for the timely detection of hydrogen leaks. Here we report an ultrafast (0.4 s) hydrogen detection system based on a wafer-scale fabrication process. It consists of a low power (20.2 mW) hydrogen sensor based on vertical thermal conduction structure and a signal processing circuit introduced with a neural network prediction algorithm based on sensor response process. The fabricated sensor exhibits rapid response, wide detection range, and wide operating temperature, while showing good long-term stability and excellent selectivity. Meanwhile, the model significantly enhanced the detection speed by enabling hydrogen concentration prediction using only the initial 40 data points (sampling frequency of 100 Hz) from the sensor response before the sensor completes the entire response process. This work introduces a novel approach to achieve an ultrafast hydrogen detection system, which demonstrates significant application promise in the fields of low-power sensors and rapid gas detection.
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http://dx.doi.org/10.1021/acssensors.4c03487 | DOI Listing |
Inorg Chem
March 2025
College of Chemistry and Chemical Engineering,Inner Mongolia Key Laboratory of Rare Earth Catalysis, Inner Mongolia University, Hohhot 010021, China.
In this work, an Eu coordination polymer () was synthesized by a single-crystal-to-single-crystal transformation based upon complex under the stimulation of water molecules ({[Eu(bpdc)(HO)]·4HO} (), {[Eu(bpdc)(HO)]·5HO} (), and Hbpdc = 2,2'-bipyridine-3,3'-dicarboxylic acid ligand). Complex exhibited considerable pH fluorescence stability in an aqueous solution. Notably, the experiment showed that complex achieved high selectivity and sensitivity for the detection of the notorious food additive melamine (MEL) through a significant fluorescence enhancement response; and yet complex had no fluorescent response with MEL.
View Article and Find Full Text PDFBiomed Chromatogr
April 2025
Cambrex High Point, High Point, North Carolina, USA.
A quality by design (QbD)-based high-resolution, stability-indicating high-performance liquid chromatography (HPLC) method was developed for determining impurities in loperamide hydrochloride (LPH) tablet dosage forms. Using this method, eight known impurities were qualified, and three degradants were quantified with excellent peak resolution. Mobile Phase-A consisted of 0.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
February 2025
INTERRA, School of Technology, Universidad de Extremadura, Cáceres 10003, Spain. Electronic address:
This study investigates the non-covalent interactions between both the free and tautomeric forms of 5-fluorouracil (5-FU) and poly(lactic-co-glycolic acid) (PLGA) nanoparticles through density functional dispersion correction (DFT-D) at the B3LYP-D level in a dichloromethane (DCM) and water environments. Our results indicate that the non-covalent interactions formed between the carbonyl and amide groups of the free form of 5-FU and the carboxyl group of PLGA facilitate a rapid initial release of the drug, aligning with experimental findings. The calculated binding energies for 5-FU in its keto-enol (-0.
View Article and Find Full Text PDFACS Sens
March 2025
State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China (UESTC), Chengdu 610054, China.
Hydrogen detection plays a crucial role in various scenes of hydrogen energy such as hydrogen vehicles, hydrogen transportation and hydrogen storage. It is essential to develop a hydrogen detection system with ultrafast response times (<1 s) for the timely detection of hydrogen leaks. Here we report an ultrafast (0.
View Article and Find Full Text PDFAnal Chem
March 2025
State Key Laboratory for Quality and Safety of Agro-Products, School of Material Science and Chemical Engineering, Ningbo University, Ningbo 315211, P. R. China.
A target-triggered, enzymatic cascade-amplified low-field nuclear magnetic resonance (LF-NMR) sensor was developed for the detection of the circulating tumor cell (CTC) A549. A multifunctional two-dimensional bionanomaterial GDA@GOX&DNA1 was designed as the initiator, with FeO@DNA2/Apt as the recognition unit and CaO@MnO as the signal unit. When A549 was present, the aptamer (Apt) detached from the recognition unit, allowing the formation of GDA@GOX&DNA1-DNA2@FeO and triggering the following reactions: (1) glucose oxidase (GOX) catalyzed the reaction between the substrate glucose and oxygen (O) to produce gluconic acid and hydrogen peroxide (HO); (2) the generated acid and HO reacted with MnO, producing signal probes Mn and O; and (3) CaO reacted with the acid, generating HO.
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