This study evaluates the efficacy of adjuvant cisternostomy (AC) versus decompressive craniectomy (DC) in managing severe traumatic brain injury (sTBI). A single-center retrospective analysis of consecutive sTBI patients treated with AC or DC alone (2018-2019) revealed that the AC group exhibited significantly lower intracranial pressure and higher Glasgow Coma Scale scores compared with the DC group (P < .05). Cerebrospinal fluid and serum analyses demonstrated reduced interleukin-1β and nerve fiber layer levels in the AC group. In addition, the AC group required lower mannitol dosages and showed fewer postoperative complications. Six-month follow-up indicated a statistically higher rate of good prognosis in the AC group (P < .05). These findings suggest that AC is superior to DC in reducing intracranial pressure, mitigating neurological damage, and improving clinical outcomes in sTBI patients.
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Effect of adjuvant cisternostomy on the prognosis of patients with severe traumatic brain injury: A single center's retrospective study.
Medicine (Baltimore)
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Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
This study evaluates the efficacy of adjuvant cisternostomy (AC) versus decompressive craniectomy (DC) in managing severe traumatic brain injury (sTBI). A single-center retrospective analysis of consecutive sTBI patients treated with AC or DC alone (2018-2019) revealed that the AC group exhibited significantly lower intracranial pressure and higher Glasgow Coma Scale scores compared with the DC group (P < .05).
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