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Racial Differences in Discrepancies Between Subjective Ratings and Objective Assessments of Hearing Impairment.
Gerontologist
January 2025
School of Aging Studies, University of South Florida, Tampa, Florida, USA.
Background And Objectives: To better understand racial/ethnic disparities in hearing aid use, we examined racial differences in discrepancies between subjective hearing ratings and objective hearing tests as a potential source of this disparity.
Research Design And Methods: A cross-sectional assessment was conducted using the data from the Health and Retirement Study (HRS). Our analytic sample included 2,568 participants aged 50 and older: 1,814 non-Hispanic White Americans and 754 non-Hispanic Black Americans.
Cochlear Organ Dissection, Immunostaining, and Confocal Imaging in Mice.
Bio Protoc
January 2025
ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
The organ of Corti, located in the inner ear, is the primary organ responsible for animal hearing. Each hair cell has a V-shaped or U-shaped hair bundle composed of actin-filled stereocilia and a kinocilium supported by true transport microtubules. Damage to these structures due to noise exposure, drug toxicity, aging, or environmental factors can lead to hearing loss and other disorders.
View Article and Find Full Text PDFWnt signalling facilitates neuronal differentiation of cochlear Frizzled10-positive cells in mouse cochlea via glypican 6 modulation.
Cell Commun Signal
January 2025
Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, 250022, China.
Degeneration of cochlear spiral ganglion neurons (SGNs) leads to irreversible sensorineural hearing loss (SNHL), as SGNs lack regenerative capacity. Although cochlear glial cells (GCs) have some neuronal differentiation potential, their specific identities remain unclear. This study identifies a distinct subpopulation, Frizzled10 positive (FZD10+) cells, as an important type of GC responsible for neuronal differentiation in mouse cochlea.
View Article and Find Full Text PDFNumber of children and dementia risk: a causal mediation analysis using data from the HUNT study linked with national registries in Norway.
BMC Neurol
January 2025
Department for Physical Health and Aging, Norwegian Institute of Public Health, Oslo, Norway.
Background: Childlessness, as well as having a high number of children, has been reported to be associated with an elevated risk of dementia compared to having 2-3 children. The mechanisms underlying these relationships are not well understood and may be mediated by different midlife risk factors. We examined the mediating role of various factors on the relationship between the number of children and dementia risk.
View Article and Find Full Text PDF"It was frightening because it could be my own grandparents": A qualitative study of vicarious exposure to anti-Asian racism.
Psychol Trauma
January 2025
Department of Medicine, Section of General Internal Medicine, University of Chicago.
Objective: From the beginning of the COVID-19 pandemic, there has been a proliferation of anti-Asian racism. In addition to being personal targets of racism, members of the Asian American community have also been vicariously exposed to repeated news and social media stories about anti-Asian racism. Emerging research suggests that vicarious exposure to racism during the pandemic is associated with decreased well-being, although mechanisms of action are not yet clear.
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