Introduction: While the enthusiasm for artificial intelligence (AI) to enhance surgical decision-making continues to grow, the preceding advance of risk prediction tools (RPTs) has had limited impact to date. To help inform the development of AI-powered tools, we evaluated the role of RPTs and prevailing attitudes among urologists.
Methods: We conducted a national mixed methods study using a sequential explanatory design. Through the 2019 AUA Census, we surveyed urologists on RPT use, helpfulness, and trust. Based on responses, we interviewed 25 participants on RPTs, risk evaluation, and surgical decision-making. Coding-based thematic analysis was applied and integrated with survey findings.
Results: Among 2,081 urologic surgeons (weighted sample 12,366), 30.4% (95% CI 28.2-32.6%) routinely used RPTs and 34.3% (95% CI 31.9-36.6%) found them helpful while 47.0% (95% CI 44.6-49.5%) generally trusted their own assessment over RPT-generated estimates. More years in practice was negatively associated with RPT use, helpfulness, and trust (p<0.001). Qualitatively, participants described relying on their intuition for surgical risks and benefit and employing gist-based approximations rather than numerical information, which RPTs provide. RPT helpfulness centered on risk/benefit confirmation, calibration, and communication, but methodological (e.g., individual vs. group estimates, missing variables) and operational (e.g., ease of use, clinical workflow) challenges limit greater RPT use.
Conclusions: Despite their wide availability, RPTs remain limited in their use and helpfulness. This reflects both the intuitive nature of surgical decision-making and implementation challenges. For AI to reach its promise and improve surgical care and outcomes, both types of barriers will need to be addressed.
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http://dx.doi.org/10.1097/UPJ.0000000000000808 | DOI Listing |
Ann Med
December 2025
Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Background: Despite the high prevalence of mental stress among physicians, reliable screening tools are scarce. This study aimed to evaluate the capability of the Physician Well-Being Index (PWBI) in identifying distress and adverse consequences among Chinese physicians.
Methods: This cross-sectional online survey recruited 2803 physicians from Southern Mainland China snowball sampling between October and December 2020.
J Clin Lipidol
February 2025
Fatty Acid Research Institute, Sioux Falls, SD, USA (Drs Tintle, Marchioli, and Harris); Department of Internal Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, USA (Dr Harris).
Background: Accurate predictive tools are crucial for identifying patients at increased risk for atherosclerotic cardiovascular disease (ASCVD). The Pooled Cohort Equation (PCE) is commonly used to predict 10-year risk for ASCVD, but its accuracy remains imperfect.
Objective: This study examined the extent to which the omega-3 index (O3I; the proportion of eicosapentaenoic acid+docosahexaenoic acid in erythrocyte membranes) improved the predictive capability of PCE.
JACC Cardiovasc Interv
March 2025
Clinical Trials Center, Cardiovascular Research Foundation, New York, New York, USA; Division of Cardiology, Department of Medicine, Columbia University Medical Center/NewYork-Presbyterian Hospital, New York, New York, USA.
Background: Severe calcification is the morphology most strongly associated with stent underexpansion.
Objectives: The aim of this study was to revise an optical coherence tomography (OCT)-derived calcium score to predict stent underexpansion in severely calcified lesions (angle >270°) using a point-based system.
Methods: A retrospective observational study was conducted in which 250 de novo lesions undergoing OCT-guided stenting, with angiographically visible calcium and optical coherence tomographic maximum superficial calcium angle >270°, not subjected to atherectomy or specialty balloon treatment before stent implantation, were randomly divided into derivation (n = 167) and validation (n = 83) cohorts.
JACC Cardiovasc Interv
March 2025
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany.
A global treatment algorithm was developed for the endovascular revascularization of femoropopliteal lesions and chronic total occlusions, aiming toward a more standardized approach to endovascular treatment in patients with peripheral artery disease. The following steps are proposed. 1) Evaluation of lesion morphology based on preprocedural imaging by Duplex sonography and intravenous ultrasound for selection of lesion preparation tools.
View Article and Find Full Text PDFJ Genet Eng Biotechnol
March 2025
Department of Bioinformatics, Pharmacogenomics and CADD Lab, Alagappa University, Karaikudi, Tamil Nadu, India. Electronic address:
Hypertension is the foremost modifiable risk factor for cardiovascular and renal diseases, and overall mortality on a global scale. Genetic variants have the potential to alter an individual's drug responses. In the present study, we employed a comprehensive computational analysis to evaluate the structural and functional implications of deleterious missense variants to examine the influence of RAAS genes such as AT1R, AT2R, and MasR on susceptibility to hypertension.
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