Take home messages 1. Despite being considered a benign tumor, the high reported incidence of embolic events increasingly warrants surgical resection, regardless of size, especially in patients with a history of cardiovascular risk factors. 2. Multimodal imaging evaluation plays a crucial role in distinguishing intracardiac masses, relying on the physician's ability to discern characteristic findings. Proper assessment leads to appropriate management decisions based on suggestive findings.
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Université Grenoble Alpes, Université Savoie Mont Blanc, CNRS, LPNC, Grenoble, France. Electronic address:
The advancements in understanding hemispheric specialization of language (HSL) have been following two primary avenues: the development of neuroimaging techniques and the study of its reorganizations in patients with various neuropathologic conditions. Hence, the objectives of this chapter are twofold. First, to provide an overview of the key neuroimaging techniques employed to investigate HSL, along with the notable findings derived from them in the healthy population.
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Int J Cardiol
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Université Paris Cité, Department of Cardiology, University Hospital of Lariboisiere, (Assistance Publique des Hôpitaux de Paris, AP-HP), 75010 Paris, France; Inserm MASCOT - UMRS 942, University Hospital of Lariboisiere, 75010 Paris, France; MIRACL.ai laboratory, Multimodality Imaging for Research and Analysis Core Laboratory and Artificial Intelligence, University Hospital of Lariboisiere (AP-HP), 75010 Paris, France.
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Evaluating tissue distribution of Positron Emission Tomography (PET) tracers during their development conventionally involves autoradiography techniques, where radioactive compounds are used for visualization and quantification in tissues during preclinical development stages. Mass Spectrometry Imaging (MSI) offers a potential alternative, providing spatial information without the need for radioactivity with a similar spatial resolution. This study aimed to optimize a MSI sample preparation protocol for assessing PET tracer candidates with a focus on two compounds: UCB-J and UCB2400.
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