FIRST REPORT OF TUMORS IN GARDEN DORMICE ().

J Zoo Wildl Med

Research Institute of Wildlife Ecology, Department of Interdisciplinary Life Sciences, University of Veterinary Medicine Vienna, 1160 Vienna, Austria.

Published: March 2025

The garden dormouse is listed as "near threatened" on the IUCN Red List of threatened species. Research on this species concentrates primarily on their hibernating strategies and physiology. However, little is known about infectious entities in this species, even less about neoplastic diseases. This case series presents the first report of different neoplasms in a population of garden dormice () under human care. This report includes six animals (four males, two females, four to seven years old). Four animals were euthanized, and two were found dead in the enclosure. Tissues of the animals were stained with Hematoxylin and eosin. Special staining (methyl green pyronin, desmin, vimentin, and cytokeratin) was performed to confirm diagnoses. Tumors found in these animals consisted of a pancreatic adenocarcinoma, a plasma cell tumor, an osteosarcoma, and three sarcomas. Because of their declining population trend and efforts of reintroduction, knowledge about diseases is imperative, especially, if there might be a genetic influence, which could hinder the success of conservation efforts.

Download full-text PDF

Source
http://dx.doi.org/10.1638/2023-0095DOI Listing

Publication Analysis

Top Keywords

garden dormice
8
report tumors
4
tumors garden
4
dormice garden
4
garden dormouse
4
dormouse listed
4
listed "near
4
"near threatened"
4
threatened" iucn
4
iucn red
4

Similar Publications

FIRST REPORT OF TUMORS IN GARDEN DORMICE ().

J Zoo Wildl Med

March 2025

Research Institute of Wildlife Ecology, Department of Interdisciplinary Life Sciences, University of Veterinary Medicine Vienna, 1160 Vienna, Austria.

The garden dormouse is listed as "near threatened" on the IUCN Red List of threatened species. Research on this species concentrates primarily on their hibernating strategies and physiology. However, little is known about infectious entities in this species, even less about neoplastic diseases.

View Article and Find Full Text PDF

The garden dormouse (Eliomys quercinus) is a fat-storing mammal that undergoes annual periods of hibernation to mitigate the effects of food scarcity, low ambient temperatures, and reduced photoperiod that characterize winter. Like other hibernating species, this animal suppresses its metabolic rate by downregulating nonessential genes and processes in order to prolong available energy stores and limit waste accumulation throughout the season. MicroRNAs (miRNAs) are short, single-stranded, noncoding RNAs that bind to mRNA and mediate post-transcriptional suppression, making miRNA ideal for modulating widespread changes in gene expression, including global downregulation typified by metabolic rate depression.

View Article and Find Full Text PDF

Novel polyomavirus in the endangered garden dormouse Eliomys quercinus.

Virol J

November 2024

Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio al. 7, Vilnius, LT-10257, Lithuania.

Article Synopsis
  • The garden dormouse's population in Europe has declined significantly due to factors like habitat loss, climate change, and potentially pathogen exposure.
  • In a study involving 89 garden dormice from Germany, researchers tested kidney samples for polyomavirus DNA and checked for antibodies in their body fluids.
  • A new polyomavirus related to other known polyomaviruses was identified, with a small percentage of dormice testing positive for the virus, suggesting that further research is needed to determine its significance and specificity to the garden dormouse.
View Article and Find Full Text PDF

Hibernation is a period of metabolic suppression utilized by many small and large mammal species to survive during winter periods. As the underlying cellular and molecular mechanisms remain incompletely understood, our study aimed to determine whether skeletal muscle myosin and its metabolic efficiency undergo alterations during hibernation to optimize energy utilization. We isolated muscle fibers from small hibernators, and and larger hibernators, and .

View Article and Find Full Text PDF

Telomere dynamics in hibernating species are known to reflect seasonal changes in somatic maintenance. Throughout hibernation, the periodic states of rewarming, known as inter-bout euthermia or arousals, are associated with high metabolic costs including shortening of telomeres. In the active season, if high energetic resources are available, telomere length can be restored in preparation for the upcoming winter.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!