Real-World Evidence (RWE), as an important pillar of Integrated Evidence Plans (IEP), offers a promising tool to address numerous hurdles impeding patients to receive timely and adequate treatments.
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Fan therapy for breathlessness - how do you do it and why?
Curr Opin Support Palliat Care
March 2025
Wolfson Palliative Care Research Centre, University of Hull, Hull, East Yorkshire, UK.
Purpose Of The Review: This review summarises high-level evidence for fan therapy and adds a commentary on the relatively-neglected question of how to optimise benefits based on qualitative evidence, clinical experience and broader research and theory.
Recent Findings: Recent high-level evidence suggests the fan reduces time to recovery from episodic breathlessness rather than reduces daily levels over a longer period. Lower grade evidence suggests the fan can also help people increase their physical activity.
Effect of chewing gum on clinical outcomes and postoperative recovery in adult patients after gastrointestinal surgery: an umbrella review.
Int J Surg
March 2025
Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Background: Gastrointestinal surgery is crucial for many medical conditions but can lead to difficult recoveries. Chewing gum is proposed as a remedy, yet existing reviews offer conflicting results. This umbrella review aims to synthesize the effectiveness of chewing gum on time to first flatus, time to first bowel movement, length of stay and complication rates in adult patients.
View Article and Find Full Text PDFMultinuclear Silver(I)-Selenium Clusters Formation in Selenopeptides.
Inorg Chem
March 2025
Université de Pau et des Pays de l'Adour, E2S UPPA, CNRS, IPREM, 2 Avenue du Président Pierre Angot, Pau 64053, France.
The reactions of ionic silver (Ag) with arginine vasopressin (AVP), a nonapeptide hormone cyclized by two cysteine residues, and its diselenium analogue was explored by an integrated LC-MS, UV-vis, and DFT approach. The replacement of Cys by SeCys in AVP increased the reactivity of the peptide toward Ag ions under mildly reducing conditions, with the formation of a SeAg cluster provided by Ag(I)-mediated dimerization of diselenide AVP. Specific electronic absorption bands confirmed the formation of the Agpeptide complex, supported by DFT calculations.
View Article and Find Full Text PDFAdvancing dental education with technology: The integration of smartphone applications in endodontics-A narrative review.
Int Endod J
March 2025
Department of Restorative and Reconstructive Dentistry, The Sydney Dental School, The University of Sydney, Surry Hills, New South Wales, Australia.
Background: Smartphone applications are increasingly used in medical and dental education, offering flexible and interactive learning opportunities. In medicine, these tools enhance knowledge retention, clinical decision-making, and patient care.
Objective: This review aims to evaluate the role of smartphone applications in endodontic education, assessing their quality, functionality, perceived impact, usability, and impact on learning outcomes.
Criteria and prognostic factors for survival and success rates for autotransplantation in the area of first and second molars.
Swiss Dent J
March 2025
Riga Stradiņš University, Faculty of Dentistry.
Autotransplantation of immature third molars is an effective treatment option, offering high success rates, minimal complications, and notable improvements in occlusal function and dental aesthetics. This study aims to review and evaluate the available evidence specifically on the survival and success rates of immature autotransplanted third molars and to identify prognostic factors that influence these outcomes. A comprehensive search was conducted in the Elsevier Journals (ScienceDirect), MEDLINE (PubMed), and Dentistry & Oral Sciences Source (EBSCOhost) databases up to May 2024.
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