Sex differences in the risk factors, diagnosis, treatment, and outcomes of patients with cardiovascular disease have been well described; however, the bulk of the literature has focused on heart disease in women. Data on sex differences in peripheral vascular disease are ill defined, and there is a need to report and understand those sex-related differences to mitigate adverse outcomes related to those disparities. Although peripheral vascular disease is a highly diverse group of disorders affecting the arteries, veins, and lymphatics, this scientific statement focuses on disorders affecting the peripheral arteries to include the aorta and its branch vessels. The purpose of this scientific statement is to report the current status of sex-based differences and disparities in peripheral vascular disease and to provide research priorities to achieve health equity for women with peripheral vascular disease.
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http://dx.doi.org/10.1161/CIR.0000000000001310 | DOI Listing |
Sex differences in the risk factors, diagnosis, treatment, and outcomes of patients with cardiovascular disease have been well described; however, the bulk of the literature has focused on heart disease in women. Data on sex differences in peripheral vascular disease are ill defined, and there is a need to report and understand those sex-related differences to mitigate adverse outcomes related to those disparities. Although peripheral vascular disease is a highly diverse group of disorders affecting the arteries, veins, and lymphatics, this scientific statement focuses on disorders affecting the peripheral arteries to include the aorta and its branch vessels.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
February 2025
Department of ENT & HNS, Command Hospital (EC), Kolkata, India.
To differentiate central vertigo mimicking peripheral vestibular diseases with proper history taking, examination and imaging to enable early diagnosis and management. This was an Observational Study carried out over two years and targeted patients across all age groups presenting with complaints of vertigo in ENT OPD of hospitals of the Armed Forces. All patients in all age groups for both genders were included, even those who had presented with recurring symptoms having been managed conservatively elsewhere.
View Article and Find Full Text PDFJ Anat
March 2025
Curtin Medical School, Curtin University, Perth, Western Australia, Australia.
The vasa vasorum (VV) have gathered considerable interest over the last decade due to its role in vascular wall biology and pathology; however, while the coronary VV are relatively well studied, the anatomy of peripheral VV, such as those of the aorta, remains poorly described, hampering knowledge of their role in peripheral vascular diseases. Through careful retrieval of the porcine thoracic aorta and successful microthrombi removal, the thoracic aorta was perfused with BriteVu™ followed by micro-computed tomography (micro-CT) scanning to image the VV and obtain a 3D reconstruction. We used commercially available software and its thresholding algorithms.
View Article and Find Full Text PDFArthritis Res Ther
March 2025
Department of Rheumatology and Immunology, Capital Medical University Affiliated Anzhen Hospital, Beijing, China.
Objectives: Takayasu arteritis (TAK) is an inflammatory vasculitis that affects the aorta and its primary branches. The pathogenesis of TAK remains elusive, yet identifying key cell types in the aorta of TAK patients is crucial for uncovering cellular heterogeneity and discovering potential therapeutic targets.
Methods: This study utilized single-cell transcriptome analysis on aortic specimens from three TAK patients, with control data sourced from a publicly available database (GSE155468).
Cardiol Young
March 2025
Department of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Introduction: Vitamin D is crucial for normal organ function, vascular health and exercise performance, yet its deficiency is widespread. Patients with CHD often exhibit reduced exercise capacity. Limited research exists on vitamin D in CHD.
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