Biological lasers, representing innovative miniaturized laser technology, hold immense potential in the fields of biological imaging, detection, sensing, and medical treatment. However, the reported gain media for biological lasers encounter several challenges complex preparation procedures, high cost, toxicity concerns, limited biocompatibility, and stability issues along with poor processability and tunability. These drawbacks have impeded the sustainable development of biological lasers. Carbon dots (CDs), as a novel solution-processable gain materials characterized by facile preparation, low cost, low toxicity, excellent biocompatibility, high stability, easy modification, and luminescence tuning capabilities along with outstanding luminescence performance. Consequently, they find extensive applications in diverse fields such as biology, sensing, photoelectricity, and lasers. Henceforth, they are particularly suitable for constructing biological lasers. This paper provides a comprehensive review on the classification and application of existing biological lasers while emphasizing the advantages of CDs compared to other gain media. Furthermore, it presents the latest progress made by utilizing CDs as gain media and forecasts both promising prospects and potential challenges for biological lasers based on CDs. This study aims to enhance understanding of CD lasers and foster advancements in the field of biological lasers.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/adma.202418118 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics.
J Allergy Clin Immunol
March 2025
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minn. Electronic address:
Background: The few reported patients with pathogenic IRF8 variants have manifested 2 distinct phenotypes: (1) an autosomal recessive severe immunodeficiency with significant neutrophilia and absence of or significant decrease in monocytes and dendritic cells and (2) a dominant-negative form with only a decrease in conventional type 2 dendritic cells (cDC2s) and susceptibility to mycobacterial disease.
Objectives: Genetic testing of a child with persistent EBV viremia identified a novel IRF8 variant: c.1279dupT (p.
Interfacial-Design Mediated Construction of Hybrid Multicompartment Architectures with Layered Physicochemical Barriers for Separately Sequestration of Oxidation-Reduction Molecules and Their Redox Reaction Regulation.
Small
March 2025
College of Food Science, Southwest University, Chongqing, 400715, China.
Hybrid multicompartment artificial architectures, inherited from different compartmental systems, possess separate microenvironments that can perform different functions. Herein, a hybrid compartmentalized architecture via hybridizing ferritin nanocage (Fn) with non-aqueous droplets using aminated-modified amphiphilic gelatin (AGEL) is proposed, which enables the generation of compartmentalized emulsions with hybrid multicompartments. The resulting compartmentalized emulsions are termed "hybrasome".
View Article and Find Full Text PDFSingle-Calibration Cell Size Measurement With Flow Cytometry.
Cytometry A
March 2025
School of Life Sciences, University of Warwick, Coventry, UK.
Measuring the size of individual cells in high-throughput experiments is often important in biomedical research and applications. Nevertheless, popular tools for high-throughput single-cell biology, such as flow cytometers, only offer proxies of a cell's size, typically reported in arbitrary scales and often subject to changes in the instrument's settings as selected by multiple users. In this paper, we demonstrate that it is possible to calibrate flowcytometry laser scatter signals with accurate measures of cell diameter from separate devices and that the calibration can be conserved upon changes in the laser settings.
View Article and Find Full Text PDFA PEGylated conjugated-BODIPY oligomer for NIR-II imaging-guided photothermal therapy.
J Mater Chem B
March 2025
Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Shanghai 200237, China.
The integration of second near-infrared (NIR-II) fluorescence imaging and photothermal therapy (PTT) achieved precise and efficient tumor treatment. BODIPY, a promising fluorescent dye, is widely used in biological fluorescence imaging due to its excellent optical properties and chemical stability. However, the excitation wavelengths of BODIPY typically range from 530 nm to 650 nm within the visible spectrum, which significantly limits tissue penetration.
View Article and Find Full Text PDFSimultaneous Application of Methylene Blue and Chlorin e6 Photosensitizers: Investigation on a Cell Culture.
Sovrem Tekhnologii Med
March 2025
PhD, Senior Researcher, Laser Biospectroscopy Laboratory, Light-Induced Surface Phenomena Department, Natural Sciences Center; Prokhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilov St., Moscow, 119991, Russia; Associate Professor, Department 87 "Laser Micro-, Nano-, and Biotechnologies, Engineering Physics Institute for Biomedicine"; National Research Nuclear University MEPhI, 31 Kashirskoye Highway, Moscow, 115409, Russia.
Unlabelled: The application of photosensitizers for inhibition of oxidative phosphorylation in order to temporally decrease oxygen uptake by tumor cells in the course of photodynamic therapy (PDT) evokes growing interest. is to overcome tumor hypoxia for further photodynamic therapy with simultaneous use of type I photosensitizer methylene blue (MB) and type II photosensitizer chlorin e6.
Material And Methods: A photodynamic activity of MB and its combined use with chlorin e6 has been studied on the HeLa cell culture, their effect on cell metabolism in their co-accumulation and subsequent irradiation has also been assessed.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!