Ewing's sarcoma (ES) is a small round cell tumor that mainly involves the skeleton, with an incidence of 2.93 per million. It is responsible for 4-10% of all bone tumors, with long bones and pelvis being the most frequently observed locations, whereas it affects the skull in only about 1-4% of cases. After osteosarcoma, ES is the most frequently observed bony primary malignant tumour in children. It more frequently regards adolescents or young adults. It is rarely diagnosed below 5 years of age or after the age of 30. ES rarely occurs in the head and neck district and, when it occurs, the jaw and skull base are the two most frequently involved locations. Clinically, head and neck ES does not show any pathognomonic finding, with the most frequent signs and symptoms usually due to the mass effect of the neoplasm. The aim of this paradigmatic case report is to present and discuss the diagnosis and management of a rare case of ES of the right pterygo-palatine region in a 5-year-old girl, that had been previously misdiagnosed and managed as a dental abscess.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890478 | PMC |
http://dx.doi.org/10.1007/s12070-024-05199-1 | DOI Listing |
Ann Med
December 2025
Department of Neonatology, Children's Hospital of Soochow University, Suzhou, China.
Aim: This review aims to summarize the epidemiology, pathogenesis, clinical features, management, prognosis and regression of Neonatal lupus erythematosus (NLE) with a view to providing directions for standardized diagnosis, treatment and further research.
Methods: We conducted a comprehensive literature review of NLE. NLE-related peer-reviewed papers were searched through PubMed/Medline were searched up to November 2024.
Rev Esp Enferm Dig
March 2025
General Practitioner, University of Americas, Brazil.
Intestinal polyps have been described in association with chronic schistosomiasis, and must be differentiated from malignant tumors and appropriately managed. This uncommon condition may be very rarely detected in people from non-endemic areas of this zoonosis, who were occasionally infected during some travel period. The lesions are more frequently described in men, and predominating in the colon.
View Article and Find Full Text PDFTransfusion
March 2025
Israel Defense Forces Medical Corps, Surgeon General's Headquarters, Israel Defense Forces, Ramat Gan, Israel.
Background: Thoracic injuries are a leading cause of morbidity and mortality in military trauma. Tension pneumothorax (TPX) is a critical diagnosis that can lead to rapid hemodynamic and respiratory collapse if untreated. While timely intervention is essential, prehospital TPX diagnosis is challenging and may lead to unnecessary interventions.
View Article and Find Full Text PDFEpidemiol Prev
March 2025
Center for Nursing Research and Innovation (CeNRI), Università Vita-Salute San Raffaele, Milano.
Background: urge urinary incontinence (UUI) is the involuntary loss of urine accompanied or immediately preceded by a sudden and strong desire to urinate that cannot be delayed or that is difficult to postpone. Data claim that UUI increases significantly from 40 to 65 years, which is why this specific age group, which has been little studied in the literature, deserves to be investigated. Moreover, they are socially active and working women who represent a social and economic resource for the country: therefore, their malaise is not only a personal problem, but also a problem for the society.
View Article and Find Full Text PDFHum Vaccin Immunother
December 2025
Department of Research & Development, Yither Biotech Co Ltd, Shanghai, China.
The World Health Organization (WHO) has recently declared another global health emergency due to the rapidly spreading monkeypox (Mpox) outbreak in numerous African countries. To address the unmet need to contain the outbreak using the existing vaccines, this study developed a lyophilization process for an effective, scalable and affordable Mpox mRNA-LNP vaccine candidate to address the global health crisis. A comprehensive evaluation and optimization of the vaccine formulation (the type/concentration of cryoprotectants, the type/concentration of buffer system, as well as the mRNA concentration and reconstitution solvent) and the freeze-drying process parameters (freezing method, temperature, cooling rate and primary/secondary drying conditions) were conducted.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!