Background: Chronic obstructive pulmonary disease (COPD) has become a major global healthcare issue due to its high prevalence and mortality rates. Increasing evidence suggests that autophagy plays a role in the development of COPD, yet there is a lack of bibliometric analyses on literature related to autophagy and COPD. Therefore, this study aims to summarize the current research status, research direction, and research hotspots in the literature related to COPD and autophagy.
Methods: A search was conducted on the Web of Science Core Collection for literature related to COPD and autophagy from October 2004 to October 2024. Subsequently, bibliometric and visualization analyses were performed on the included publications using R software, CiteSpace, and VOSviewer.
Results: A total of 481 published articles across 229 journals related to COPD and autophagy were included. During the study period, there was a trend of continuous growth in both the annual number of publications and citations in this field. The United States had the highest centrality, while China was the most productive country. Major research institutions included Maastricht University, Harvard University, and Jikei University. The American Journal of Physiology-Lung Cellular and Molecular Physiology, International Journal of Chronic Obstructive Pulmonary Disease, and Autophagy are the most influential journals in this field. The author with the most published papers is Araya J, while Choi AMK is the most influential author. Frequently appearing keywords include "oxidative stress," "obstructive pulmonary disease," "aging," "apoptosis," and "mitophagy."
Conclusion: This bibliometric study helps researchers quickly understand the research overview of autophagy and COPD, thus providing new insights and directions for future research in this field.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891039 | PMC |
http://dx.doi.org/10.3389/fmed.2025.1514686 | DOI Listing |
Clinicoecon Outcomes Res
March 2025
CliCon S.r.l., Società Benefit, Health, Economics & Outcomes Research, Bologna, 40137, Italy.
Purpose: To describe patients with hormone receptor positive and human epidermal growth factor receptor 2 negative metastatic breast cancer (HR+/HER2- mBC) in Italy for demographic and clinical variables, comorbidity profile, metastases and therapeutic pathways.
Patients And Methods: From 2017 to 2021, HR+/HER2- mBC patients were extrapolated from administrative databases of healthcare entities covering a catchment area of about 3 million health-assisted women. The study included patients with a hospital discharge diagnosis for mBC; with specific prescriptions of therapies for HR+; without HER2-targeted therapy; with at least one prescription for CDK4/6 inhibitors.
Int J Chron Obstruct Pulmon Dis
March 2025
College of Basic Medical Sciences, Jilin University, Changchun, 130021, People's Republic of China.
COPD is a multifactorial illness characterized by a long-term restriction of airflow and an inflammatory reaction in the lungs. The associated emphysema leads to the breakdown of alveolar proteins and abnormal expansion of the lung air spaces. Chronic bronchitis caused by the same disease can result in increased deposition of structural proteins, narrowing of the airways, and excessive mucus secretion leading to acute exacerbation of COPD (AECOPD).
View Article and Find Full Text PDFInt J Chron Obstruct Pulmon Dis
March 2025
Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden, Lund University, Lund, Sweden.
Background: Severe alpha-1-antitrypsin deficiency (AATD) is a known risk factor for early development of emphysema and COPD. By the Swedish national screening program within the years 1972-74 a cohort of individuals with severe AATD (PiZZ) was identified and regularly followed up. The aim of this study was to investigate alveolar volume (V) and the ratio V/Total lung capacity (V/TLC) for the detection of signs of hyperinflation and ventilation heterogeneity in PiZZ individuals compared with an age-matched control group (phenotype PiMM), randomly selected from the population registry.
View Article and Find Full Text PDFBackground: Chronic obstructive pulmonary disease (COPD) has become a major global healthcare issue due to its high prevalence and mortality rates. Increasing evidence suggests that autophagy plays a role in the development of COPD, yet there is a lack of bibliometric analyses on literature related to autophagy and COPD. Therefore, this study aims to summarize the current research status, research direction, and research hotspots in the literature related to COPD and autophagy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!