Pethidine, Maybe a Rearrangement in the Pharmaceutical Group Is Needed!

Iran J Pharm Res

Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Published: December 2024

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892746PMC
http://dx.doi.org/10.5812/ijpr-156667DOI Listing

Publication Analysis

Top Keywords

pethidine rearrangement
4
rearrangement pharmaceutical
4
pharmaceutical group
4
group needed!
4
pethidine
1
pharmaceutical
1
group
1
needed!
1

Similar Publications

Opioid properties of some derivatives of pethidine based on tropane.

J Pharm Pharmacol

October 1992

School of Pharmacy and Pharmacology, University of Bath, Claverton Down, UK.

The preparation of some tropane analogues of pethidine and its reversed ester, chiefly with preferred 3 alpha-m-hydroxyphenyl chair conformations, is described. The former were secured from tropan-3-one in a sequence of reactions involving cyanide attack, hydrolysis, Grignard attack and then rearrangements. The reversed ester was obtained by treating tropan-3-one with lithium phenyl, followed by acylation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!