Allergic fungal rhinosinusitis is a non-invasive form of highly recurrent chronic rhinosinusitis. A probable correlation between fungal sinusitis, a disorder resulting from fungal infections of the sinuses that can worsen nasal symptoms and complicate treatment, and allergic rhinitis has been shown by recent investigations. The aim of this study is to estimate the prevalence of fungal sinusitis among allergic rhinitis patients. This cross-sectional study was conducted among 150 patients with chronic Allergic sinusitis who were attending the ENT, Outpatient Department at a Tertiary Care Hospital. All patients were subjected to an X-ray of the Paranasal sinuses followed by diagnostic nasal endoscopy, then a fungal smear and culture were done. Demographic details, Comorbidities, symptoms and DNE findings were collected and analysed using SPSS v.21. The prevalence of fungal sinusitis in cases of allergic rhinitis was 25.3%. fungal sinusitis was found to be more common among the patients with aged 45 years above and the patients with comorbidities. We found an Association between fungal sinusitis with comorbidities (0.001). Patients with allergic rhinitis are more likely to experience fungal sinusitis. For people with allergic rhinitis, a fungal sinusitis diagnosis and prompt treatment are essential to reducing symptoms and improving quality of life.
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http://dx.doi.org/10.1007/s12070-024-05256-9 | DOI Listing |
Indian J Otolaryngol Head Neck Surg
February 2025
Department of Otorhinolaryngology (ENT), Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamilnadu 603103 India.
Allergic fungal rhinosinusitis is a non-invasive form of highly recurrent chronic rhinosinusitis. A probable correlation between fungal sinusitis, a disorder resulting from fungal infections of the sinuses that can worsen nasal symptoms and complicate treatment, and allergic rhinitis has been shown by recent investigations. The aim of this study is to estimate the prevalence of fungal sinusitis among allergic rhinitis patients.
View Article and Find Full Text PDFVet Ophthalmol
March 2025
Ophthalmology Section, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
A 15-year-old Swiss Warmblood gelding was presented to the ophthalmology service of Zurich University due to severe visual impairment. Ophthalmic and neurologic examinations were performed, raising suspicion of post-retinal blindness. Standing contrast computed tomography (CT) of the head revealed a partially calcified, soft tissue attenuating mass in the sphenopalatine sinus with concurrent compression of the optic nerves and chiasm.
View Article and Find Full Text PDFFront Immunol
March 2025
Research & Development, Citryll B.V., Oss, Netherlands.
Eosinophils are a subset of granulocytes that protect the host against fungal and parasitic infection through secretion of their granular contents. In response to specific stimuli, eosinophils also undergo a type of lytic cell death, referred to as eosinophil extracellular trap (EET)-associated cell death (EETosis), where histone citrullination facilitates chromatin decondensation, cell rupture and release of pro-inflammatory, decondensed chromatin into the extracellular environment as EETs. In this study, we show the abundant presence of eosinophils and citrullinated histones in nasal polyp tissue of patients with eosinophilic chronic rhinosinusitis (ECRS).
View Article and Find Full Text PDFDiagn Microbiol Infect Dis
May 2025
Department of Pathology, Chosun University College of Medicine, Gwangju, South Korea. Electronic address:
Objective: To describe a rare case of invasive fungal sinusitis caused by Malassezia restricta in a patient with diabetes and emphasize the diagnostic difficulties and significance of molecular techniques.
Study Design: An 85-year-old man with diabetes presented with unresolved left sphenoiditis despite a sphenoidotomy and antibiotics. Imaging findings indicated invasive fungal sinusitis.
J Pediatr Hematol Oncol
March 2025
Microbiology Laboratory, Beilinson Hospital, Rabin Medical Center, Petach Tikva.
Invasive fungal diseases significantly impact hemato-oncology pediatric patients, with Aspergillus and Candida being the primary culprits. However, pediatric Alternaria infections remain understudied. This study aims to characterize Alternaria infections in pediatric hemato-oncology cases nationwide.
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