Papillary thyroid carcinoma is the most common thyroid malignancy, with a higher incidence in women. Vitamin D deficiency has been proposed as a potential risk factor for various cancers, including thyroid cancer. This study investigates the association between vitamin D deficiency and papillary thyroid carcinoma. A retrospective cross-sectional study was conducted on 209 patients diagnosed with papillary thyroid carcinoma from January 2016 to December 2020. Clinical data, including vitamin D levels, were collected and analyzed using SPSS software. ANOVA was employed to determine the significance of the relationship between vitamin D status, lymph node positivity, and thyroid nodule size. Vitamin D deficiency was prevalent in 58.4% of patients, with 25.4% being insufficient and 16.3% normal. No significant relationship was found between vitamin D levels and the number of positive lymph nodes ( = 0.457) or thyroid nodule size ( = 0.775). Vitamin D levels may not be a reliable prognostic indicator for papillary thyroid carcinoma. Further research with larger sample sizes is necessary to explore this association.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890653 | PMC |
| http://dx.doi.org/10.1007/s12070-024-05225-2 | DOI Listing |
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