A series of star-shaped poly[2-(methacryloyloxy)ethyl trimethylammonium chloride]s with different arm lengths were synthesized open-aired enzymatically assisted ATRP using the 2-hydroxypropyl β-cyclodextrin derivative as an initiator. The resulting PMETAs with narrow molecular weight distribution ( = 1.06-1.12) created thin hydrophilic films with thickness < 40 nm exhibiting water contact angle (WCA) values < 50°. Higher interfacial tension values obtained for star-shaped polymers in comparison with the linear analog indicate that surface wettability can be modified by changing the polymer topology. AFM was used to analyze the relationship between macromolecule topology, surface roughness, and WCA.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892006 | PMC |
| http://dx.doi.org/10.1039/d5ra00674k | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Open-aired synthesis of star-shaped poly[2-(methacryloyloxy)ethyl trimethylammonium chloride].
RSC Adv
March 2025
Department of Physical Chemistry and Technology of Polymers, Faculty of Chemistry, Silesian University of Technology M. Strzody 9 Street 44-100 Gliwice Poland
A series of star-shaped poly[2-(methacryloyloxy)ethyl trimethylammonium chloride]s with different arm lengths were synthesized open-aired enzymatically assisted ATRP using the 2-hydroxypropyl β-cyclodextrin derivative as an initiator. The resulting PMETAs with narrow molecular weight distribution ( = 1.06-1.
View Article and Find Full Text PDFSupramolecular Polycations with a Linear-Star Architecture Containing Hydrophobic Poly[(,)-3-hydroxybutyrate]: Formation of DNA Micelleplexes Coated with Apolipoprotein E3 for Blood-Brain Barrier Penetrating Gene Delivery.
Biomacromolecules
March 2025
Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, 15 Kent Ridge Crescent, Singapore 119276, Singapore.
A novel blood-brain barrier (BBB)-penetrating supramolecular gene delivery system was developed utilizing a host-guest block-building strategy to systematically screen and optimize various block compositions. Linear poly(ethylene glycol) (PEG) was coupled with hydrophobic poly[(,)-β-hydroxybutyrate] (PHB) blocks of varying lengths with an adamantyl (Ad) end, giving the PEG-PHB-Ad guest polymers, which were complexed with the cationic 4-arm star-shaped β-cyclodextrin-poly(2-dimethylaminoethyl methacrylate) (βCD-pDMAEMA) host polymer, resulting in the formation of linear-star pseudoblock PEG-PHB-Ad/βCD-pDMAEMA copolymers. These amphiphilic supramolecular copolymers were thoroughly characterized and assessed for the formation of DNA micelleplex nanoparticles as a gene delivery system.
View Article and Find Full Text PDFPresenting Antimicrobial Peptides on Poly(ethylene glycol): Star-Shaped vs Comb-Like Architectures.
Macromolecules
February 2025
Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia 22903, United States.
Conjugating antimicrobial peptides (AMPs) to nonlinear polymers is a promising strategy to overcome the translational challenges of AMPs toward treating infections caused by antibiotic-resistant bacteria. Nonlinear polymers, and therefore conjugates, can be prepared with various architectures (e.g.
View Article and Find Full Text PDFThe Development and Preparation of Novel Gel Emulsion Systems Based on a Cholesterol Star-Shaped Derivative.
Molecules
February 2025
School of Chemistry and Environment Science, Shaanxi University of Technology, Hanzhong 723001, China.
Low-molecular-mass gelators (LMMGs) as stabilizers for gel emulsions offer numerous advantages, such as low usage, functionalizability, and insensitivity to phase ratio. Using LMMGs as stabilizers is one of the effective strategies for preparing gel emulsions. Currently, developing LMMGs and stable gel emulsion systems in a rapid and convenient manner remains a challenge.
View Article and Find Full Text PDFSynthesis and Self-Assembly of Pore-Forming Three-Arm Amphiphilic Block Copolymers.
Macromol Rapid Commun
February 2025
Department of Chemistry, Saarland University, 66123, Saarbrücken, Germany.
The synthesis of an amphiphilic three-arm block copolymer (AB)-BCP, which consists of poly(methyl methacrylate) (PMMA) and poly(butyl methacrylate) (PBMA) in the hydrophobic inner block, is reported. The hydrophilic block segment is based on poly(2-hydroxyethyl methacrylate) (PHEMA) originating from 2-(trimethylsiloxyl)ethyl methacrylate (HEMA-TMS). The preparation is carried out in two steps using a core-first approach.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!