Miliary spread of mesothelioma is a rare but important manifestation of late-stage disease, likely due to hematogenous dissemination. This case highlights characteristic CT imaging findings, emphasizing the need for awareness among clinicians and radiologists. Recognizing this pattern can aid in diagnosis, prognostication, and appropriate referral for palliative management.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891395PMC
http://dx.doi.org/10.1002/rcr2.70141DOI Listing

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Miliary spread of mesothelioma is a rare but important manifestation of late-stage disease, likely due to hematogenous dissemination. This case highlights characteristic CT imaging findings, emphasizing the need for awareness among clinicians and radiologists. Recognizing this pattern can aid in diagnosis, prognostication, and appropriate referral for palliative management.

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Case of a 57-Year-Old Man With Malignant Mesothelioma Presenting With Miliary Nodules on Chest Imaging.

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November 2021

Department of Pulmonary and Critical Care Medicine, Allegheny Health Network, Pittsburgh, PA. Electronic address:

A 57-year-old man with history of stage IIIB right-sided malignant pleural mesothelioma was admitted from his oncologist's office for progressive dyspnea of two weeks duration. He had associated dyspnea at rest and a new dry cough. He denied sputum production, hemoptysis, or fevers, but he did endorse chills, fatigue, and weight loss.

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Well-differentiated papillary mesothelioma: A 17-year single institution experience with a series of 75 cases.

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February 2019

Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

We present our experience with 75 cases of well-differentiated papillary mesothelioma (WDPM) that were diagnosed at our institution between 2000 and 2017. The patients included 58 females and 17 males with age ranging from 18 to 69 years (mean, 42 years). Clinically, the vast majority of WDPMs were incidental findings during laparotomy or laparoscopic surgery for a variety of benign or malignant disease.

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Well-differentiated papillary mesothelioma of the peritoneum (WDPMP) is a rare subtype of epithelioid mesothelioma, which is usually seen in young women without a history of asbestos exposure, and generally, has an indolent course. The relative rarity of this neoplasm in males prompted us to report this case of a well-differentiated papillary mesothelioma of the peritoneum in a 36-year-old man. The patient, who had no history of asbestos exposure, presented with abdominal pain and ascites of unknown etiology.

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Article Synopsis
  • Malignant pleural mesothelioma (MPM) is an aggressive cancer that usually affects the pleura around the lungs, often leading to serious complications like respiratory failure and weight loss.
  • A unique case involved a 73-year-old man with a history of asbestos exposure, diagnosed with MPM alongside miliary pulmonary metastases and nephrotic syndrome, demonstrating unusual manifestations of the disease.
  • Despite chemotherapy, the patient’s condition worsened with additional health issues, ultimately leading to his death; this case is considered the first documented instance of MPM associated with both pulmonary metastases and nephrotic syndrome.
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