Background: The COVID-19 pandemic has had a negative impact on the population's mental health, particularly for individuals with health anxiety (HA) and obsessive compulsive disorder (OCD). This is in conjunction with a significant change in accessibility of face-to-face psychological services which have had to rapidly adapt to the remote delivery of therapy.
Aims: Using a single-arm open trial design, the study aimed to evaluate the effectiveness of evidence-based CBT interventions for HA and OCD delivered via a blend of online therapist consultations interspersed with self-study reading materials. A secondary aim was to evaluate remote training workshops provided to therapists.
Method: Therapists attended three half-day remote workshops after which consecutive participants with HA or OCD were assigned to therapists for treatment. Monthly expert supervision was provided. Patients completed routine outcome measures at each session and an idiosyncratic measure of pre-occupation with COVID-19 at pre- and post-treatment.
Results: Significant and comparable improvements were observed on measures of anxiety, depression and social adjustment from pre- to post-treatment in both the HA (=14) and OCD (=20) groups. Disorder-specific measures also showed significant improvements after treatment. The HA group showed greater levels of change on the COVID-19-specific questionnaire. The training workshops were well received by therapists, who valued the monthly supervision sessions.
Conclusions: The study provides support for the effectiveness of the online delivery of CBT for HA and OCD supported by the inclusion of additional self-study booklets.
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http://dx.doi.org/10.1017/S1352465824000511 | DOI Listing |
JAMA Psychiatry
March 2025
Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Importance: Expectancy effects are significant confounding factors in psychiatric randomized clinical trials (RCTs), potentially affecting the interpretation of study results. This narrative review is the first, to our knowledge, to explore the relationship between expectancy effects, compromised blinding integrity, and the effects of active treatment/placebo in psychiatric RCTs. Additionally, we present statistical and experimental approaches that may help mitigate the confounding impact of expectancy effects.
View Article and Find Full Text PDFAltern Ther Health Med
March 2024
Context: Postpartum care primarily focuses on the mother's physical recuperation, encompassing the prevention and treatment of postpartum ailments. However, healthcare practitioners have relatively neglected the psychological needs of mothers. Postpartum depression (PPD) is a psychological health concern that necessitates attention and timely intervention.
View Article and Find Full Text PDFPsychophysiology
March 2025
Department of Clinical and Health Psychology, University of Florida, Gainesville, USA.
Reductions in both the size of the amygdala and functional activity during emotional processing have been independently associated with trauma exposure and severity, raising the question of whether reduced volume prompts reduced functional activation. In this multimodal assessment, the relationship between amygdala structure and function was investigated in mood and anxiety patients to determine their covariation and their relationship to trauma magnitude. Overall, amygdala volume and functional emotional reactivity were unrelated, with smaller volumes and reduced emotional reactivity each independently predicting trauma magnitude for women, and mediation analysis did not support a hypothesis that the relationship between reduced functional activity and trauma severity depends on amygdala volume.
View Article and Find Full Text PDFJ Prim Care Community Health
March 2025
Mayo Clinic, Rochester, MN, USA.
Objective: This study evaluated the feasibility and satisfaction of using a wearable brain activity sensing device for stress reduction among patients experiencing Long COVID (LC).
Patients And Methods: Patients with LC (N = 45) were invited to participate in an open-label pilot study. Participants were asked to use a brain-sensing electroencephalogram (S-EEG) wearable device (Muse-S™) daily for 90 days and followed for an additional 90 days (180 days total participation).
J Opioid Manag
March 2025
Department of Practice, Sciences, and Health Outcomes Research, University of Maryland School of Pharmacy, Baltimore, Maryland. ORCID: https://orcid.org/0000-0002-3397-9679.
Objective: To deploy an algorithm using medical and pharmacy claims data to identify members of a managed care organization at risk for opioid misuse and provide outreach.
Methods: A retrospective review of 2019 enrollment information and prescription and medical claims data identified members aged 18-64 years with medical and pharmacy benefits and at least one paid pharmacy claim for an opioid. The most recent paid prescription claim served as the index date for each patient.
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