Background: Family caregivers of psychiatric patients often experience various negative psychosocial consequences, with a decline in quality of life being the most prevalent. This study was conducted with the aim of evaluating the psychometric indices of the Persian version of the Family Caregiver-Specific Quality of Life Scale (FAMQOL).
Methods: This cross-sectional study was conducted in 400 family caregivers of patients with chronic psychiatric diseases in Iran in 2024 using convenience sampling. Using a forward-backward translation procedure, the face and content validity of the FAMQOL were assessed through both qualitative and quantitative methods. After face and content validity, in order to determine construct validity, exploratory (n = 200) and confirmatory (n = 200) factor analysis was performed. To determine reliability, internal consistency (Cronbach's alpha coefficient and Macdonald's omega coefficient) and stability (intraclass correlation coefficient) were estimated.
Results: A total of 400 participants were evaluated, comprising 184 males (46.0%) and 216 females (54.0%). In content validity, one item was removed and during exploratory factor analysis, the remaining 15 items were loaded on four factors including social, spiritual, physical and psychological, which described 61.74% of the total variance. Confirmatory factor analysis showed that the obtained model has a good fit. All obtained factors had convergent and discriminant validity. Cronbach's alpha (0.783 to 0.932), Macdonald's omega (0.817 to 0.934) and intraclass correlation coefficients (0.953 to 0.971) showed acceptable internal consistency and stability of the factors of the Persian version of FAMQOL.
Conclusion: Findings from this study confirm that the Persian version of the FAMQOL is a valid and reliable instrument for evaluating the quality of life among family caregivers of patients with chronic psychiatric disorders. This scale holds significant potential for both research and clinical applications, facilitating the identification of caregivers' needs and guiding the creation of targeted interventions to enhance their quality of life.
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http://dx.doi.org/10.1186/s40359-025-02528-z | DOI Listing |
J Cutan Med Surg
March 2025
Division of Dermatology, Department of Medicine, Queen's University, Kingston, ON, Canada.
Background: For optimal control of atopic dermatitis (AD), patient education is essential to complement traditional therapy. Patient education has proven to benefit AD outcomes, but previous methods of delivery are costly and time-consuming.
Objective: To assess the effectiveness of a one-page pictorial education tool at improving AD quality of life (QoL) and disease severity.
J Cutan Med Surg
March 2025
Division of Dermatology, University of Alberta, Edmonton, AB, Canada.
Calcinosis cutis, characterized by the pathological deposition of insoluble calcium salts in the skin, is associated with several disease entities, particularly autoimmune conditions such as scleroderma and dermatomyositis. Lesions of calcinosis are often painful, prone to ulceration, and significantly impair quality of life. Despite the clinical impact, no effective treatments have been established to date, making prevention of this condition a critical priority.
View Article and Find Full Text PDFJAMA Cardiol
March 2025
Department of Cardiovascular Medicine and Section on Geriatrics and Gerontology, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Importance: Excess body fat plays a pivotal role in the pathogenesis of heart failure with preserved ejection fraction (HFpEF). HU6 is a novel, controlled metabolic accelerator that enhances mitochondrial uncoupling resulting in increased metabolism and fat-specific weight loss.
Objective: To assess efficacy and safety of HU6 in reducing body weight, improving peak volume of oxygen consumption (VO2) and body composition among patients with obesity-related HFpEF.
Curr Opin Support Palliat Care
March 2025
Department of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Purpose Of Review: Two widely validated health-related quality of life (HR-QoL) tools, specifically designed for patients with advanced cancer, are the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 15 Palliative Care (EORTC QLQ-C15-PAL) and the Functional Assessment of Chronic Illness Therapy-Palliative (FACIT-Pal-14). This systematic review aims to evaluate the use of EORTC QLQ-C15-PAL and FACIT-Pal-14 in prospective studies in patients with advanced cancer, focusing on study types, clinical settings, additional HR-QoL tools used, and completion rates.
Recent Findings: Sixty studies were included in the analysis.
JAMA Netw Open
March 2025
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.
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