Current radiotherapy machines intended to perform streamlined online adaptive therapy are designed to be standalone, which makes it challenging to integrate them with the rest of the clinic. This work describes the installation of a standalone CT-guided online adaptive system, the Varian Ethos, in a busy clinic utilizing products from multiple vendors, including RayStation as the treatment planning system (TPS) and MOSAIQ as the oncology information system (OIS). The aim was to develop solutions that minimized workload increases for staff using redundant systems and to implement this new technology safely, with no increase in safety reports resulting from its integration into the clinic. The Ethos was delivered with a pre-configured beam model, and a separate Ethos beam model was developed in RayStation 10A. Non-adaptive treatments were planned in RayStation and transferred to Ethos for delivery. Although MOSAIQ 2.64 could not communicate with the Ethos, a machine characterization file was developed to allow manual recording of the treatment fields in MOSAIQ. Online adaptive therapy was performed using the Ethos TPS and OIS with documentation in MOSAIQ. Although dose calculations of the same plans differed by 1%-2% in the pelvis in RayStation compared to the Ethos TPS, dose computed in both systems passed measurement-based QA, end-to-end testing, and clinical trial credentialing, so both systems were commissioned for clinical use. RayStation plans were successfully modified for delivery on Ethos, and at go-live, all non-adaptive planning was performed in RayStation and adaptive planning in Ethos. Ethos treatments were documented in MOSIAQ, which remained the OIS of record for all patients. Monitoring of error reports indicated some unique failure modes to the new technology, but the overall number of safety reports remained comparable to other systems. In conclusion, Ethos was successfully deployed for both non-adaptive and online adaptive therapy in a multi-vendor environment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/acm2.70033 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Medication misuse is a threat to public health and patient safety, and strategies to prevent medication misuse should be incorporated in nursing education.
Method: An interdisciplinary nursing and pharmacy team collaborated on a pilot project with graduate FNP students to adapt and evaluate a training program for pharmacy students on the prevention of medication misuse for nursing based on the publicly available online program Generation Rx.
Results: Of 39 students who participated in the training, 74% ( = 29) completed pre- and posttest surveys.
Outreach by Municipal Public Health Nurses to Vulnerable Pregnant Women During the COVID-19 Pandemic: A Qualitative Study.
Cureus
February 2025
Research Institute of Nursing Care for People and Community, University of Hyogo, Akashi, JPN.
Background: The coronavirus disease 2019 (COVID-19) pandemic posed substantial challenges for public health nurses (PHNs) in delivering outreach services to vulnerable pregnant women and families requiring assistance. Despite restrictive measures, the importance of maintaining face-to-face support and implementing adaptive strategies was evident.
Objectives: This study aimed to identify the key characteristics of outreach practices conducted by PHNs during the pandemic, the challenges they encountered, and the strategies needed to address these issues effectively.
Comprehensive in-silico characterization and expression pattern of calmodulin genes under various abiotic and biotic stresses in Indian mustard ().
Physiol Mol Biol Plants
February 2025
Plant Engineering and Stress Adaptomics Lab, Department of Botany, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh India.
Unlabelled: Calcium (Ca⁺) as a secondary messenger has a multidimensional role, including the growth and development of plants and the adaptive response to stress conditions. Calmodulin (CaM), a calcium-binding protein, uniquely binds with these Ca⁺ ions and transmits Ca⁺ signals. Calmodulin proteins have been well-reported in various plants for playing a role in abiotic and biotic stress signaling; however, a comprehensive analysis of the genes of Indian mustard () has not been studied much.
View Article and Find Full Text PDFEXPRESS: Does Information Predicting "When" and "What" Facilitate Target Detection Interactively?
Q J Exp Psychol (Hove)
March 2025
Graduate School of Informatics, Kyoto University, Kyoto, JAPAN.
Human responses to environmental stimuli are essential for adapting to surroundings. Cue informativeness (how accurately a cue provides information about events requiring an action) can be pivotal in guiding behavior. Similarly, timing predictability (the extent to which people can predict when events will occur) influences their responses.
View Article and Find Full Text PDFThe mediating role of health literacy in the relationship between trust in public health authorities and distrust in health systems.
BMC Public Health
March 2025
Faculty of Humanities and Social Sciences, Department of Translation and Interpretation, Ondokuz Mayıs University, Samsun, Turkey.
Background: This study addresses a gap in the literature by examining how health literacy mediates the relationship between trust in public health authorities and distrust in health systems, particularly in the Turkish context. While previous studies have examined trust and health literacy separately, few have examined trust in health systems regarding health literacy and trust in public health authorities. Therefore, the primary purpose of this study is to determine the mediating role of health literacy in the relationship between trust in public health authorities and distrust in the health system.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!