Background: Rapid deployment aortic valve replacement (RDAVR) has been widely adopted, but concerns about postoperative paravalvular leak (PVL) associated with its use remain. PVL is linked to an increased risk of long-term mortality; however, there is no consensus on its treatment.
Case Presentation: Case 1: A 76-year-old female with severe aortic stenosis underwent RDAVR via median sternotomy. Intraoperative transesophageal echocardiography (TEE) revealed moderate PVL at the left-noncoronary cusp commissure. Three horizontal mattress stitches were applied from outside the aorta through the prosthetic sewing cuff to address the PVL site; however, the leak persisted. It was noted that the balloon-expandable sealing frame was slightly protruding inward at a location corresponding to the PVL site. Accordingly, balloon dilatation was performed under direct vision, and the PVL resolved. Postoperatively, no conduction disorders were observed. At the 24-month follow-up, echocardiography showed no recurrence of PVL. Case 2: A 78-year-old male with severe aortic stenosis underwent RDAVR in a standardized fashion. Intraoperative TEE revealed moderate PVL at the right coronary cusp side. The balloon-expandable sealing frame was found not to have fully expand outward at the PVL site. Balloon dilatation was therefore performed as in Case 1, successfully resolving the PVL. No postoperative conduction disorder was encountered. At the 12-month follow-up, echocardiography revealed no recurrent PVL.
Conclusions: Direct intraoperative re-ballooning is a potentially effective option for addressing intraoperatively identified PVL after RDAVR.
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http://dx.doi.org/10.1186/s44215-025-00198-2 | DOI Listing |
Gen Thorac Cardiovasc Surg Cases
March 2025
Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, 980-8574, Japan.
Background: Rapid deployment aortic valve replacement (RDAVR) has been widely adopted, but concerns about postoperative paravalvular leak (PVL) associated with its use remain. PVL is linked to an increased risk of long-term mortality; however, there is no consensus on its treatment.
Case Presentation: Case 1: A 76-year-old female with severe aortic stenosis underwent RDAVR via median sternotomy.
Front Cell Infect Microbiol
February 2025
Department of Orthopedics, Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Objective: The aim of this study was to investigate the effect of vacuum sealing drainage (VSD) treatment on surgical indicators, inflammatory factors, and functional recovery in patients with chronic osteomyelitis secondary to open tibial fractures.
Methods: In total, 87 patients with secondary bone infection after internal fixation of tibial fracture treated in the Affiliated Hospital of Shandong Second Medical University from December 2020 to June 2022 were selected, all of whom were tibial shaft fractures. Of these, 55 cases of primary open fracture were sutured in the first stage; 32 cases underwent internal fixation after primary debridement at the time of trauma.
Sensors (Basel)
August 2024
Shandong Provincial Key Laboratory of Marine Environment and Geological Engineering, Ocean University of China, Qingdao 266100, China.
Micromachines (Basel)
August 2024
Engineering Research Center, Ministry of Education on Integrated Circuit Packaging and Testing, Tianshui 741001, China.
The key technologies for the ultrathin small outline package (TSOP) of large-sized high-speed chips have been designed and developed in this paper. The designing techniques, such as a 25 µm precise positioning dice attaching technique, a lead frame unit structure without a base island, and a lead co-plane layout inside the frame, were developed. The TSO package outline with a large number of leads, a frame unit arrangement, and a frame distribution with a base island and without one were improved.
View Article and Find Full Text PDFDent J (Basel)
June 2024
Unit of Endodontics and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
(1) Background: Pulp canal obliteration (PCO) is a common condition characterized by an abnormal dentinal apposition within the canal wall, which often rises as a consequence of dental trauma. In recent years, "guided endodontics" has offered a reliable and safer procedure for endodontic access in case of PCO. The present case report aims to introduce a new endodontic guided system with a sleeveless, open-frame titanium guide designed to reduce costs compared to traditional templates.
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