Objective: Patient education at the time of discharge using models which aim to improve self-care behaviors can significantly contribute to patients' adoption of a healthy lifestyle and treatment adherence. This is a randomized controlled clinical trial with no blinding in which we tested two groups of intervention control. 90 patients having undergone coronary angioplasty were allocated to an intervention (N = 45) and a control group randomly (N = 45). Data were collected from January to October 2022. The data collection instruments comprised angioplasty patients' treatment adherence questionnaire, Walker's health-promoting lifestyle profile questionnaire, and Snyder's Hope Scale. Data analysis was performed using SPSS version 23. To analyze the data, we used descriptive statistics. Accordingly, inferential statistics applied included chi-square, independent-samples t-test, and repeated measures (ANOVA). Significance level was considered as p < 0.05.
Results: The mean scores of lifestyle, hope, and treatment adherence in the intervention group were significantly higher than those of the control group as measured immediately and three months after the intervention (p < 0.05). The study results revealed that using discharge program based on Orem's self-care model positively impacted the lifestyle, hope, and treatment adherence of patients having experienced coronary angioplasty.
Iranian Registry Of Clinical Trials: IRCT registration number: IRCT20190917044802N5.
Registration Date: 17/7/2022.
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http://dx.doi.org/10.1186/s13104-025-07164-9 | DOI Listing |
AIDS Care
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Center for Behavioral and Addiction Medicine, Department of Family Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Methamphetamine use among sexual minority men (SMM) has been associated with poor ART adherence, and reduced initiation and adherence to PrEP. From May 2021 to May 2023, 226 SMM were enrolled in , a culturally responsive smartphone application to reduce methamphetamine use and improve sexual health. Using a status-neutral approach, an ordinal variable reflected participants' placement on the HIV Prevention/Care Continuum, from HIV-positive, not taking ART, to HIV-negative, currently taking PrEP.
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March 2025
Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Gyeonggi-do, Seongnam-si, 13620, Republic of Korea, 82 317877085.
Background: Ward rounds are an essential component of inpatient care. Patient participation in rounds is increasingly encouraged, despite the occasional complicated circumstances, especially in acute care settings.
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Blood
March 2025
Vanderbilt UniversityVanderbilt-Meharry Center of Excellence in Sickle Cell Disease, Nashville, Tennessee, United States.
Recurrent ischemic priapism is a common complication of sickle cell anemia (SCA) and is associated with devastating physical and psychosocial consequences. All previous trials for priapism prevention have failed to demonstrate clear efficacy. We conducted a randomized, controlled, double-blind phase 2 feasibility trial comparing fixed moderate-dose hydroxyurea plus placebo (usual care arm) versus fixed moderate-dose hydroxyurea plus tadalafil (experimental arm) in 64 men (18- 40 years) with at least three episodes of SCA-related priapism in the past 12 months.
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Department of Planned Immunization, Chaoyang District Centre for Disease Control and Prevention, Beijing, China.
Assessing knowledge of HPV and HPV vaccine and vaccine willingness among Beijing secondary school parents, and identifying decision-influencing factors. Selected via multi-stage stratified sampling, 3,081 Chaoyang secondary school students' parents participated in a June-August 2024 study. They completed a questionnaire assessing HPV knowledge, vaccine awareness, and vaccination willingness.
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March 2025
Team "Staphylococcal Pathogenesis", CIRI - Centre International de Recherche en Infectiologie, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Lyon, France.
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of sight-threatening infections in the US. These strains pose a significant challenge in managing ocular infections, as they frequently exhibit resistance to first-line empirical antibiotics. To assess the potential of bacteriophages as innovative topical therapies for treatment of recalcitrant ocular infections, we evaluated the in vitro antimicrobial activity of a set of anti-S.
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