Background: Obsessive-compulsive disorder (OCD) is a disabling disorder, and self-stigma negatively impacts quality of life, symptom severity and self-esteem. esTOCma is a smartphone-based serious game developed to increase knowledge about OCD and reduce stigma. It features 10 missions using psychoeducation, indirect contact and cognitive restructuring. Players help 10 characters escape the OCD stigma monster.
Aims: To explore, in individuals with a self-reported diagnosis of OCD, the feasibility, acceptability and preliminary effectiveness of esTOCma to change self-stigma and knowledge about OCD, OC severity, guilt, quality of life and self-esteem.
Materials And Methods: A single-arm pilot study with 130 participants who completed esTOCma and pre-, post- and 3-month follow-up assessments.
Results: Half of participants spent 9-10-days playing with the app and most of them found it useful/very useful and easy to use. Self-stigma was associated with higher OC symptoms, guilt and lower quality of life, self-esteem and knowledge about OCD. After using the app, participants showed lower levels of self-stigma, OC symptoms and guilt, and higher levels of quality of life, self-esteem and knowledge about OCD. Changes were maintained or increased at a 3-month follow-up.
Discussion: esTOCma is a feasible and acceptable app that could help people with OCD to increase their knowledge and understanding of the disorder, dismiss self-stigma and OC symptoms, and at the same time increase self-esteem and quality of life. A replication of the study with a control sample is needed to validate our findings.
Conclusion: Tools like the esTOCma app, accessible 24/7, offer a means to tackle self-stigma detrimental effects.
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http://dx.doi.org/10.1111/bjc.12537 | DOI Listing |
Ann Ig
March 2025
Department of Global Public Health Policy and Governance, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
Background: Seafarers experience unique challenges related to their profession, including risks for mental health. The present study explored the correlates of depression among seafarers in India.
Methods: Following ethics clearance, this cross-sectional study was conducted at an international shipping company in Mumbai, India.
Plant Physiol
March 2025
Shanghai Collaborative Innovation Center of Agri-Seeds, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Sugar accumulation during fruit ripening is an essential physiological change that influences fruit quality. While NAC transcription factors are recognized for their role in modulating strawberry (Fragaria × ananassa) fruit ripening, their specific contributions to sugar accumulation have remained largely unexplored. This study identified FvNAC073, a NAC transcription factor, as a key regulator that not only exhibits a gradual increase in gene expression during fruit ripening but also enhances the accumulation of sucrose.
View Article and Find Full Text PDFEpidemiol Prev
March 2025
ISDE - Medici per l'Ambiente, sezione di Vicenza.
Objectives: to evaluate the association between exposure to per- and polyfluoroalkyl substances (PFAS) and semen quality in young adulthood, with particular attention to different exposure metrics: serum and seminal concentrations of perfluorooctanoic acid (PFOA) and perfluorosulfonic acid (PFOS), foetal exposure, duration of exposure.
Design: cross-sectional study.
Setting And Participants: 1,000 subjects aged 18-35 years residing in the Veneto area with water contamination by PFAS, enrolled in the period 2022-2023; this interim analysis involves 507 subjects out of the 1,000 enrolled.
Epidemiol Prev
March 2025
Center for Nursing Research and Innovation (CeNRI), Università Vita-Salute San Raffaele, Milano.
Background: urge urinary incontinence (UUI) is the involuntary loss of urine accompanied or immediately preceded by a sudden and strong desire to urinate that cannot be delayed or that is difficult to postpone. Data claim that UUI increases significantly from 40 to 65 years, which is why this specific age group, which has been little studied in the literature, deserves to be investigated. Moreover, they are socially active and working women who represent a social and economic resource for the country: therefore, their malaise is not only a personal problem, but also a problem for the society.
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