In heterogeneous traffic flow environments, it is critical to accurately predict the future trajectories of human-driven vehicles around intelligent vehicles in real time. This paper introduces a neural network model that integrates both spatial interaction information and the long-term and short-term characteristics of the time series. Initially, the historical state information of both the target vehicle and its surrounding counterparts, along with their spatial interaction relationships, are fed into a Graph Attention Network (GAT) encoder. The graph attention layer effectively manages the intricate relationships among vehicle nodes. Subsequently, this information undergoes processing through a Transformer encoder to extract global dependencies; additionally, residual connections are incorporated to enhance feature representation capabilities. Finally, these data are further captured by the LSTM encoder for capturing short-term features within the time series, and the LSTM decoder receives the hidden state and generates the future trajectory of the target vehicle. Validation conducted on a public dataset demonstrates that the predictive performance of this model significantly outperforms that of the baseline models.
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http://dx.doi.org/10.1038/s41598-025-93071-9 | DOI Listing |
Cytotherapy
February 2025
Health Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China. Electronic address:
Asthma, a prevalent allergic disease affecting approximately 300 million individuals globally, remains a significant public health challenge. Mesenchymal stromal cells (MSCs) and hepatocyte growth factor (HGF), both recognized for their immunomodulatory properties, hold therapeutic potential for asthma. However, their precise mechanisms remain underexplored.
View Article and Find Full Text PDFSoft Matter
March 2025
Gulliver UMR CNRS 7083, ESPCI Paris, Université PSL, 75005 Paris, France.
Colloidal particles self assemble into a wide range of structures under external AC electric fields due to induced dipolar interactions [Yethiraj and Van Blaaderen, , 2003, , 513]. As a result of these dipolar interactions, at low volume fraction the system is modulated between a hard-sphere like state (in the case of zero applied field) and a "string fluid" upon application of the field. Using both particle-resolved experiments and computer simulations, we investigate the emergence of the string fluid with a variety of structural measures including two-body and higher-order correlations.
View Article and Find Full Text PDFJ Agric Food Chem
March 2025
College of Food Science and Technology, National Center of Meat Quality and Safety Control, Nanjing Agricultural University, Nanjing 210095, China.
Costameres are essential for maintaining the integrity of muscle fibers, which affects the meat tenderness. To explore the pattern of alteration in costameres after slaughter, this study investigated the distribution of costamere proteins (desmin, talin-2, vinculin, and integrin β1), their impact on tenderness, and the involved enzymes. Western blot analysis showed that talin-2 significantly degraded in postmortem, while integrin β1 significantly increased at 48 h ( < 0.
View Article and Find Full Text PDFSoft Matter
March 2025
Sapienza University of Rome, Piazzale Aldo Moro 2, Rome, Italy.
We study a two-dimensional chiral active crystal composed of underdamped chiral active particles. These particles, characterized by intrinsic handedness and persistence, interact linear forces derived from harmonic potentials. Chirality plays a pivotal role in shaping the system's behavior: it reduces displacement and velocity fluctuations while inducing cross-spatial correlations among different Cartesian components of velocity.
View Article and Find Full Text PDFActas Esp Psiquiatr
March 2025
Department of Pediatric, The First People's Hospital of Taizhou, 318020 Taizhou, Zhejiang, China.
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and limited behavior. Despite the association of numerous synaptic gene mutations with ASD, the presence of behavioral abnormalities in mice expressing autism-associated R617W mutation in synaptic adhesion protein neuroligin-3 (NL3) has not been established. This work focuses on establishing a mouse model of ASD caused by NL3 R617W missense mutation (NL3R617W) and characterizing and profiling the molecular as well as behavioral features of the animal model.
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