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Factors influencing vaccine hesitancy among United Kingdom adolescents in a senior high school environment and actions to address it.
Hum Vaccin Immunother
December 2025
Sixth Form Department, Townley Grammar School, Bexleyheath, UK.
We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12-13 adolescents in London, UK. As the response rate was low (Cohort 1; = 112/486, 23.0%), we repeated the survey with incoming students (cohort 2, = 256/275; 93%).
View Article and Find Full Text PDF["I don't go out anymore": an analysis of voluntary social withdrawal among Italian 15-19-year-old students].
Epidemiol Prev
March 2025
Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa.
Objectives: to analyse the prevalence and characteristics of the hikikomori phenomenon in Italy within a representative sample of students aged 15 to 19 years, assessing the factors associated with this behaviour to guide preventive interventions.
Design: cross-sectional study based on anonymous data collected through the ESPAD®Italia (European School Survey Project on Alcohol and other Drugs) survey using a self-administered questionnaire.
Setting And Participants: a representative sample of Italian high-school students is selected annually to ensure the comparability of ESPAD®Italia estimates.
Large-scale evidence of a general disease ('') factor accounting for both mental and physical health disorders in different age groups.
Psychol Med
March 2025
Centre for Innovation in Mental Health, School of Psychology, University of Southampton, Southampton, UK.
Background: It is unknown whether there is a general factor that accounts for the propensity for both physical and mental conditions in different age groups and how it is associated with lifestyle and well-being.
Methods: We analyzed health conditions data from the Millennium Cohort Study (MCS) (age = 17; N = 19,239), the National Child Development Study (NCDS) (age = 44; N = 9293), and the English Longitudinal Study of Ageing (ELSA) (age ≥ 50; N = 7585). The fit of three Confirmatory Factor models was used to select the optimal solution by Comparative Fit Index, Tucker-Lewis Index, and Root Mean Square Error of Approximation.
Article Synopsis
- The study aimed to explore how plasma α-synuclein levels relate to cerebral blood flow in Parkinson's disease patients who experience freezing of gait (FOG).
- A total of 120 Parkinson's patients were assessed for FOG and divided into two groups: those with FOG and those without.
- Results showed that patients with FOG had slower blood flow in key arteries and higher α-synuclein levels, indicating that these factors independently increase the risk of FOG in Parkinson's disease.
Background: We aimed to explore the diagnostic value of chemiluminescence assay for syphilis-specific antibodies.
Methods: Clinical specimens (100 in total) were selected from patients receiving examinations from July 2022 through June 2023 and tested for syphilis-specific antigens by means of chemiluminescence assay, followed by retests through Treponema pallidum particle agglutination test (TPPA) and enzyme-linked immunosorbent assay (ELISA). A final clinical diagnosis was made in combination with the physiological conditions, underlying diseases, and other factors of the patients.
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