In radiation therapy, precise dose distribution is essential for minimizing damage to normal tissues. Gafchromic EBT3 film is widely used to assure the quality of two-dimensional dosimetry but requires frequent recalibrations due to changes in sensitivity over time. This study presents a new calibration method using a Keras-based generalized additive neural network (GANN) to address film aging. EBT3 films from four lots were calibrated with a 6 MV photon beam and scanned on Epson scanners. The GANN method achieved percentage differences between calibrated and delivered doses within 5%, comparable to traditional recalibration methods, with an overall uncertainty of approximately 2%. It demonstrated improved stability and accuracy, significantly reducing the need for frequent recalibrations and providing a robust solution for long-term film dosimetry.
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http://dx.doi.org/10.1038/s41598-025-92568-7 | DOI Listing |
Sci Rep
March 2025
Medical Physics and Informatics Laboratory of Electronics Engineering, National Kaohsiung University of Sciences and Technology, Kaohsiung, 80778, Taiwan, ROC.
In radiation therapy, precise dose distribution is essential for minimizing damage to normal tissues. Gafchromic EBT3 film is widely used to assure the quality of two-dimensional dosimetry but requires frequent recalibrations due to changes in sensitivity over time. This study presents a new calibration method using a Keras-based generalized additive neural network (GANN) to address film aging.
View Article and Find Full Text PDFBMC Cancer
February 2025
College of Nuclear Technology and Automation Engineering, Chengdu University of Technology, Chengdu, 610059, China.
Background: Treatment planning systems (TPS) often exclude immobilization devices from optimization and calculation, potentially leading to inaccurate dose estimates. This study employed deep learning methods to automatically segment 3D-printed head and neck immobilization devices and evaluate their dosimetric impact in head and neck VMAT.
Methods: Computed tomography (CT) positioning images from 49 patients were used to train the Mask2Former model to segment 3D-printed headrests and MFIFs.
Biomed Phys Eng Express
December 2024
Medical Physics Consultant, INTECNUS Foundation, RP82 8400, San Carlos de Bariloche, Río Negro, Argentina.
. To investigate the effect of the position and orientation of the detector and its influence on the determination of output factors (OF) for small fields for a linear accelerator (MR-linac) integrated with 1.5 T magnetic resonance following the TRS-483 formalism.
View Article and Find Full Text PDFJ Contemp Brachytherapy
August 2024
Department of Radiation Oncology, University of Utah, Salt Lake City, Utah, USA.
BMC Cancer
November 2024
Department of Radiation Oncology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Objective: The dose perturbation effect of immobilization devices is often overlooked in intensity-modulated radiation therapy (IMRT) for gynecologic cancer. This retrospective study assessed the dosimetric effects of a prone immobilization device combined with a belly board (PIDBB) on the skin.
Methods: We recruited 63 women with gynecologic cancer undergoing postoperative IMRT at our institute.
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