In radiation therapy, precise dose distribution is essential for minimizing damage to normal tissues. Gafchromic EBT3 film is widely used to assure the quality of two-dimensional dosimetry but requires frequent recalibrations due to changes in sensitivity over time. This study presents a new calibration method using a Keras-based generalized additive neural network (GANN) to address film aging. EBT3 films from four lots were calibrated with a 6 MV photon beam and scanned on Epson scanners. The GANN method achieved percentage differences between calibrated and delivered doses within 5%, comparable to traditional recalibration methods, with an overall uncertainty of approximately 2%. It demonstrated improved stability and accuracy, significantly reducing the need for frequent recalibrations and providing a robust solution for long-term film dosimetry.

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-025-92568-7DOI Listing

Publication Analysis

Top Keywords

gafchromic ebt3
8
ebt3 film
8
generalized additive
8
additive neural
8
frequent recalibrations
8
adaptive calibration
4
calibration gafchromic
4
film
4
film generalized
4
neural networks
4

Similar Publications

In radiation therapy, precise dose distribution is essential for minimizing damage to normal tissues. Gafchromic EBT3 film is widely used to assure the quality of two-dimensional dosimetry but requires frequent recalibrations due to changes in sensitivity over time. This study presents a new calibration method using a Keras-based generalized additive neural network (GANN) to address film aging.

View Article and Find Full Text PDF

Background: Treatment planning systems (TPS) often exclude immobilization devices from optimization and calculation, potentially leading to inaccurate dose estimates. This study employed deep learning methods to automatically segment 3D-printed head and neck immobilization devices and evaluate their dosimetric impact in head and neck VMAT.

Methods: Computed tomography (CT) positioning images from 49 patients were used to train the Mask2Former model to segment 3D-printed headrests and MFIFs.

View Article and Find Full Text PDF

. To investigate the effect of the position and orientation of the detector and its influence on the determination of output factors (OF) for small fields for a linear accelerator (MR-linac) integrated with 1.5 T magnetic resonance following the TRS-483 formalism.

View Article and Find Full Text PDF
Article Synopsis
  • A new, cost-effective surface mould for high-dose-rate cobalt-60 brachytherapy was created from medical silicone and its performance was assessed through simulations and film measurements.
  • The study found that the mould's dosimetric properties were highly consistent with treatment planning system (TPS) calculations, particularly at a depth of 0.5 cm, showing minimal discrepancies in dosage delivery.
  • Despite some variations in dose at the surface of the phantom, the mould demonstrated water equivalence at cobalt energies, indicating it can effectively be used for HDR brachytherapy treatments.
View Article and Find Full Text PDF

Objective: The dose perturbation effect of immobilization devices is often overlooked in intensity-modulated radiation therapy (IMRT) for gynecologic cancer. This retrospective study assessed the dosimetric effects of a prone immobilization device combined with a belly board (PIDBB) on the skin.

Methods: We recruited 63 women with gynecologic cancer undergoing postoperative IMRT at our institute.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!