As global energy demand grows, the oil and gas industry faces increasing challenges in optimizing production while achieving sustainability. Accurate oil well production forecasting is essential for effective resource management and operational decision-making. However, traditional mathematical models struggle with the nonlinear and dynamic characteristics of production data, while existing hybrid neural networks often lack sensitivity to operational changes and suffer from overcomplexity due to numerous parameters. This study proposes a novel hybrid model, TCN-KAN, combining temporal convolutional networks (TCN) and Kolmogorov-Arnold networks (KAN), to address these challenges. By integrating feature selection informed by reservoir engineering expertise and Spearman correlation analysis, the model effectively reduces input dimensionality while ensuring physically meaningful feature representation. Experimental results demonstrate the TCN-KAN model's superior ability to capture nonlinear interactions and long-term temporal dependencies, achieving the highest predictive accuracy among tested models. Additionally, a modified whale optimization algorithm (WOA) is employed for hyperparameter tuning, further enhancing the model's robustness. Validation on Volvo oil field data (2008-2016) highlights the model's operational sensitivity and practical value, providing actionable insights for optimizing oilfield management strategies.
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http://dx.doi.org/10.1038/s41598-025-91412-2 | DOI Listing |
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March 2025
College of Food Science, Southwest University, Chongqing, 400715, China.
Hybrid multicompartment artificial architectures, inherited from different compartmental systems, possess separate microenvironments that can perform different functions. Herein, a hybrid compartmentalized architecture via hybridizing ferritin nanocage (Fn) with non-aqueous droplets using aminated-modified amphiphilic gelatin (AGEL) is proposed, which enables the generation of compartmentalized emulsions with hybrid multicompartments. The resulting compartmentalized emulsions are termed "hybrasome".
View Article and Find Full Text PDFNanomaterials (Basel)
February 2025
Petru Poni Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Chitosan is widely used in drug delivery applications, due to its biocompatibility, bio-degradability, and low toxicity. Nevertheless, its properties can be enhanced through the physical or chemical modification of its amino and hydroxyl groups. This work explores the electrostatic complexation of two chitosan samples of differing lengths with two poly(-isopropylacrylamide) (PNIPAM) homopolymers of different molecular weight carrying a chargeable carboxyl end group.
View Article and Find Full Text PDFArtif Organs
March 2025
The BioRobotics Insitute and Department of Excellence of Robotics & AI, Scuola Superiore Sant'Anna, Pontedera, Italy.
Background: In cardiovascular engineering, the recent introduction of soft robotic technologies sheds new light on the future of implantable cardiac devices, enabling the replication of complex bioinspired architectures and motions. To support human heart function, assistive devices and total artificial hearts have been developed. However, the system's functionality, hemocompatibility, and overall implantability are still open challenges.
View Article and Find Full Text PDFBalkan J Med Genet
December 2024
University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy, Institute of pharmaceutical chemistry, Majka Tereza 47, 1000 Skopje, Republic of North Macedonia.
The loss-of-function () allele has been associated with reduced clopidogrel efficacy and increased risk of major adverse cardiovascular events (MACE). PGx-guided treatment, despite the recommendations, is not fully implemented in routine clinical practice. The primary aim of this hybrid retrospective-prospective study was to determine whether identifying LOF patients may benefit the antiplatelet drug prescribing decisions made in Kosovo.
View Article and Find Full Text PDFFront Artif Intell
February 2025
Department of Surgery, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Heart disease is a leading cause of mortality worldwide, making accurate early detection essential for effective treatment and management. This study introduces a novel hybrid machine-learning approach that combines transfer learning using the VGG16 convolutional neural network (CNN) with various machine-learning classifiers for heart disease detection. A conditional tabular generative adversarial network (CTGAN) was employed to generate synthetic data samples from actual datasets; these were evaluated using statistical metrics, correlation analysis, and domain expert assessments to ensure the quality of the synthetic datasets.
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