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Factors influencing vaccine hesitancy among United Kingdom adolescents in a senior high school environment and actions to address it.
Hum Vaccin Immunother
December 2025
Sixth Form Department, Townley Grammar School, Bexleyheath, UK.
We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12-13 adolescents in London, UK. As the response rate was low (Cohort 1; = 112/486, 23.0%), we repeated the survey with incoming students (cohort 2, = 256/275; 93%).
View Article and Find Full Text PDFThe landscape of biofilm models for phage therapy: mimicking biofilms in diabetic foot ulcers using 3D models.
Front Microbiol
February 2025
Goethe University Frankfurt, University Hospital Frankfurt, Department II of Internal Medicine, Infectious Diseases, Frankfurt, Germany.
Diabetic foot ulcers (DFU) affect up to 15-25% of patients suffering from diabetes and are considered a global health concern. These ulcers may result in delayed wound healing and chronic infections, with the potential to lead to amputations. It has been estimated that 85% of diabetes-related amputations are preceded by a diagnosis of DFU.
View Article and Find Full Text PDFUnveiling the Silent Crisis Amidst Tackling Hepatitis B in African Prisons - A Public Health Emergency.
Health Sci Rep
March 2025
Department of Veterinary Medicine, Faculty of Veterinary Medicine University of Ibadan Ibadan Nigeria.
Background: Hepatitis B is one of the major global health issues, which presents a particularly severe challenge within the confines of African prisons, characterized by high rates of transmission and limited access to adequate healthcare. The prevalence of Hepatitis B in these settings represents a silent crisis.
Objective: This research highlights the critical public health emergency posed by Hepatitis B in African prisons, underscoring the need for urgent intervention and comprehensive strategies.
The social burden of antimicrobial resistance: what is it, how can we measure it, and why does it matter?
JAC Antimicrob Resist
April 2025
Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Antimicrobial resistance (AMR) is a growing global health threat, which is increasingly quantified in terms of its human health and economic burden. In this article, we highlight that for policy and planning purposes the social burden of AMR is as important to attend to as health and economic burdens, requiring systematic consideration and measurement of multiple dimensions. We provide a conceptual and empirical overview of four dimensions of the social burden of AMR: the distribution of AMR among and between populations; the lived experiences of AMR by patients and carers; how and by whom AMR interventions are shouldered; and how AMR can change society.
View Article and Find Full Text PDFPsychometric properties of outcome measures for freezing of gait in Parkinson's disease: a systematic review and meta-analysis.
Expert Rev Pharmacoecon Outcomes Res
March 2025
Department of Human Neurosciences, Sapienza University, Rome, Italy.
Introduction: This systematic review and meta-analysis aimed to evaluate validated tools for assessing FOG in individuals with PD, focusing on their psychometric properties, linguistic adaptations, and methodological quality.
Methods: A systematic search was conducted across MEDLINE, CINHAL, SCOPUS, and Web of Science, following PRISMA-COSMIN guidelines. Studies assessing validity, reliability, and cross-cultural adaptation of FOG-specific tools were included.
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