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http://dx.doi.org/10.1016/j.ejim.2025.03.005 | DOI Listing |
Transpl Int
March 2025
Department of General Surgery, Demiroglu Bilim University and Group Florence Nightingale Hospital, Istanbul, Türkiye.
Kidney donation is a safe procedure for carefully screened donors. The growing shortage of organs and improved survival rates among recipients of living donor transplants have broadened the criteria for acceptable living donors, including older individuals and those with pre-existing health conditions. Consequently, ensuring both the short- and long-term safety of living donors is of paramount importance.
View Article and Find Full Text PDFTher Adv Musculoskelet Dis
March 2025
Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité-Universitätsmedizin Berlin, Berlin, Germany.
Background: Early treatment initiation is one of the strongest predictors of good treatment response in axial spondyloarthritis (axSpA). Recently, the Assessment in SpondyloArthritis International Society (ASAS) defined early axSpA as a diagnosis of axSpA with a duration of axial symptoms equal to or less than 2 years. Tofacitinib is a Janus kinase (JAK) inhibitor for the treatment of ankylosing spondylitis.
View Article and Find Full Text PDFClin Epidemiol
March 2025
Biomimetics and Intelligent Systems Group, Faculty of Information Technology and Electrical Engineering, University of Oulu, Oulu, Finland.
Purpose: This study applied machine learning (ML) and explainable artificial intelligence (XAI) to predict changes in HbA1c levels, a critical biomarker for monitoring glycemic control, within 12 months of initiating a new antidiabetic drug in patients diagnosed with type 2 diabetes. It also aimed to identify the predictors associated with these changes.
Patients And Methods: Electronic health records (EHR) from 10,139 type 2 diabetes patients in North Karelia, Finland, were used to train models integrating randomized controlled trial (RCT)-derived HbA1c change values as predictors, creating offset models that integrate RCT insights with real-world data.
J Pharm Health Care Sci
March 2025
Department of Cardiovascular Medicine, Tosei General Hospital, 160, Nishioiwake-cho, Seto, Aichi, 489-8642, Japan.
Background: Heart failure has a high readmission rate, but interventions by multiple professionals are effective. Although there is growing interest in the management of heart failure by community pharmacists in Japan, no effective method has been developed. We created and verified the effectiveness of a novel heart failure management protocol that community pharmacists could utilize.
View Article and Find Full Text PDFJ Physiol Anthropol
March 2025
Department of Nutrition and Food Sciences, Faculty of Agricultural and Food Sciences, American University of Beirut, Beirut, Lebanon.
Introduction: Low-intensity physical activity plays a key role in weight regulation, and reduced engagement in such activities is associated with rising obesity rates. This study explored the relationship between body fat distribution and exercise efficiency during low-intensity cycling, comparable to everyday life, focusing on adiposity in men and women.
Methods: Thirty participants (50% women and 50% men) underwent basal metabolic rate (BMR) measurements after an overnight fast.
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