Investigating the swelling behavior of superabsorbent polymer microparticles (SAP-MPs) at a single-particle level using traditional methods is constrained by low resolution and insufficient real-time data, especially for particles smaller than 300 µm. To address these challenges, a novel microfluidic device capable is developed of real-time, high-precision single-particle analysis. This platform hydrodynamically traps individual SAP-MPs, enabling continuous monitoring of their swelling dynamics under controlled conditions. SAP-MPs with varying sizes (90-270 µm), crosslinker concentrations (0.25%
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http://dx.doi.org/10.1002/marc.202500014 | DOI Listing |
Cureus
February 2025
Pulmonary and Critical Care, BronxCare Health System, Bronx, USA.
Post-extubation stridor poses a significant challenge in critical care settings, often necessitating prompt intervention to prevent respiratory compromise and potential reintubation. This case report details the successful management of post-extubation stridor in a 55-year-old female patient with a complex medical history, using heliox therapy. Heliox, a gas mixture of helium and oxygen, has emerged as a novel therapeutic option in such scenarios, owing to its ability to reduce airway resistance and improve gas flow dynamics.
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March 2025
Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612, USA.
Edema, characterized by the accumulation of interstitial fluid, poses significant challenges in various pathological conditions. Lymphangiogenesis is critical in edema clearance, and delayed or inadequate lymphatic responses significantly hinder healing processes. However, real-time observation of dynamic changes in lymphangiogenesis during tissue repair in animal models has been challenging, leaving the mechanisms behind compensatory lymphatic activation for edema clearance largely unexplored.
View Article and Find Full Text PDFMacromol Rapid Commun
March 2025
Department of Mechanical Engineering, York University, Toronto, ON, M3J 1P3, Canada.
Investigating the swelling behavior of superabsorbent polymer microparticles (SAP-MPs) at a single-particle level using traditional methods is constrained by low resolution and insufficient real-time data, especially for particles smaller than 300 µm. To address these challenges, a novel microfluidic device capable is developed of real-time, high-precision single-particle analysis. This platform hydrodynamically traps individual SAP-MPs, enabling continuous monitoring of their swelling dynamics under controlled conditions.
View Article and Find Full Text PDFSpinal cord injury (SCI) initiates a complex cascade of chemical and biophysical phenomena that result in tissue swelling, progressive neural degeneration, and formation of a fluid-filled cavity. Previous studies show fluid pressure above the spinal cord (supraspinal) is elevated for at least 3 days after injury and contributes to a phase of damage called secondary injury. Currently, it is unknown how fluid forces within the spinal cord itself (interstitial) are affected by SCI and if they contribute to secondary injury.
View Article and Find Full Text PDFCarbohydr Polym
May 2025
Institute for Advanced Ceramics, State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150001, PR China; Laboratory of Dynamics and Extreme Characteristics of Promising Nanostructured Materials, Saint Petersburg State University, St. Petersburg 199034, Russia. Electronic address:
Ionic crosslinking and Schiff base are employed to construct hydrogel wound dressings. However, the contributions of these crosslinking to the swelling behavior and adhesion performance of hydrogels are still unclear. Here, double-crosslinking chitosan hydrogel (DCH) is designed via catechol-Fe coordination and Schiff base between catechol modified chitosan and oxidized chitosan.
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