Myasthenia gravis is an autoimmune disease of the neuromuscular junctions. Studies have shown that its prevalence is slightly higher in females, that female patients are more refractory to treatment, and that their post-treatment quality of life is more difficult to improve. Recently, multiple novel treatment options have become available, and more opportunities for shared decision-making are being observed in the process of treatment selection. Thus, it is necessary to choose the best treatment for each patient through detailed explanations regarding the disease and adequate consideration of sex-based differences.
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http://dx.doi.org/10.11477/mf.188160960770030245 | DOI Listing |
J Pain Res
March 2025
Division of Pharmaceutical Evaluation and Policy, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Importance: This study addresses the critical need for an evidence-based instrument to assess the likelihood of NSAID-induced cardiovascular events, that provides clinicians with valuable decision support to improve safety in their use for pain management, especially in patients vulnerable to cardiovascular events.
Objective: To develop a practical risk scoring tool, NSAID Induced Cardiovascular Events (NAÏVE), for estimating the risk of serious cardiovascular events associated with NSAID use.
Design: Retrospective nested case-control study.
Background And Aims: Catheter-based renal denervation (RDN) is a safe and effective alternative treatment for hypertension. However, data on patient preferences are limited. This study sought to delineate preferences for RDN among Veterans with difficult-to-control hypertension at an urban VA Medical Center with the goal of optimizing management and referral practices in hypertensive Veterans.
View Article and Find Full Text PDFInt Anesthesiol Clin
April 2025
Department of Anesthesiology and Perioperative Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY.
Orphanet J Rare Dis
March 2025
Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Background: As new therapies for Duchenne muscular dystrophy (DMD) are entering the market, shared decision making (SDM) will become increasingly important. Therefore, this study aimed to understand (1) Belgian stakeholders' knowledge and perceptions of SDM in DMD treatment decision making, (2) the current state of SDM implementation in DMD in Belgium, examining the role of all involved parties, and (3) the barriers and facilitators for SDM in DMD in the Belgian context.
Methods: In this qualitative study, semi-structured interviews with the multidisciplinary team (MDT) of individuals with DMD (n = 18) and caregivers thereof (n = 11) were conducted in Belgium.
Arch Public Health
March 2025
Health Policy Research Group, University of Nigeria Enugu Campus, Enugu, Enugu state, Nigeria.
Background: Gender norms shape rights, privileges, and societal roles, impacting health and well-being. In low- and middle-income countries (LMICs), while young people may reject harmful gender discrimination, they often support other norms that perpetuate gender imbalances. This study examines factors influencing young people's attitudes toward gender norms, focusing on men's rights in decision-making, education, social roles, and equity for women's empowerment in Southeast Nigeria.
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