Background: In this study, it was aimed to investigate the relationship of circadian rhythm disorders with eating behavior and clinical features in patients diagnosed with Bipolar Disorder (BD).

Methods: The study included 95 patients with BD and a control group of 60 healthy individuals. Hamilton Depression Rating Scale (HDRS), Young Mania Rating Scale (YMRS), Eating Attitudes Test (EAT), and Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) were applied to the participants who volunteered to participate in the study.

Results: In the study, patients diagnosed with BD were compared with the healthy individuals in the control group in terms of circadian rhythms and eating behaviors. In the comparison, it was found that the total and subscale scores of BRIAN scale were higher in patients diagnosed with BD (BRIAN total score: 33.31 ± 9.30) compared to the control group (BRIAN total score: 25.07 ± 5.70). In addition, it was also observed that EAT scores were also higher in patients diagnosed with BD (EAT total score: 18.42 ± 9.11) compared to the control group (EAT total score: 14.82 ± 4.86). In the analysis of the relationship between circadian rhythms and eating behavior and clinical characteristics, it was found that circadian rhythms were associated with clinical characteristics but not with eating behavior (p = 0.785).

Conclusion: In the study, it was found that circadian rhythm disorders and eating behavior disorders were higher in patients diagnosed with BD compared to the control group. It was also observed that the deteriorated circadian rhythm was associated with clinical features.

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http://dx.doi.org/10.1016/j.jad.2025.03.020DOI Listing

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