Besides Corynebacterium diphtheriae, C. ulcerans can cause diphtheria in humans, and its incidence has been increasing alarmingly in recent years. The source and reservoir of these infections are a wide range of domestic and wild animals, in which C. ulcerans is associated with both asymptomatic carriage and sometimes severe respiratory and skin infections. The review attempts to summarize new knowledge about the pathogenicity and epidemiology of this emergent zoonotic species.
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Klin Mikrobiol Infekc Lek
June 2024
Faculty of Veterinary Medicine, University of Veterinary Science Brno, Czech Republic, e-mail:
Besides Corynebacterium diphtheriae, C. ulcerans can cause diphtheria in humans, and its incidence has been increasing alarmingly in recent years. The source and reservoir of these infections are a wide range of domestic and wild animals, in which C.
View Article and Find Full Text PDFAfter 3 cases of Corynebacterium diphtheriae infection associated with intravenous drug use among persons experiencing homelessness (PEH) were reported to the Health Protection Authority in Frankfurt am Main, Germany, in 2023, we examined pathogen spread among PEH. Furthermore, we investigated a possible link with the 2022 outbreak of diphtheria in Europe. From swab samples collected during August-November 2023 from 36 PEH and cutaneous lesions, we detected 3 additional cases of cutaneous toxigenic C.
View Article and Find Full Text PDFWe reviewed Corynebacterium spp. infection cases reported in South Africa during 2015-2023. We analyzed 84 isolates from 83 patients with C.
View Article and Find Full Text PDFAdv Protein Chem Struct Biol
February 2025
Department of Biochemistry, University of Delhi South Campus, Benito Juarez Road, Dhaula Kuan, New Delhi, India. Electronic address:
Immunotherapy is emerging as a novel and reliable therapeutic technique for treating diseases such as autoimmunity, HIV/AIDS, allergy and cancers. This approach works by modulating the patient's immune system, activating both the innate and humoral branches to combat life-threatening diseases. The foundation of immunotherapy began with the discovery and development of "serum therapy" by German physiologist Emil Von Behring who received the Nobel Prize in 1901 for his contributions to the treatment of diphtheria.
View Article and Find Full Text PDFWe report a cluster of infections with genetically related toxigenic Corynebacterium diphtheriae linked to an outbreak among asylum seekers in Switzerland that subsequently affected patients without known exposure. This discovery highlights the importance of rapid, interdisciplinary outbreak investigations and regular vaccination status assessment, especially in elderly populations with waning immunity.
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