Comprehensive approach to the rehabilitation of professionals with high levels of psychophysical stress, pain syndromes and type 2 diabetes mellitus during the war Lidiia V. Butska1,2,3, Oksana O. Drevitska1,2,3, Sergei V. Dybkalyuk4, Valentyn O. Ryzhak 5 1TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV, KYIV, UKRAINE 2INTERREGIONAL ACADEMY OF PERSONNEL MANAGEMENT, KYIV, UKRAINE 3STATE INSTITUTION «KUNDIIEV INSTITUTE OF OCCUPATIONAL HEALTH OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE», KYIV, UKRAINE 4SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE 5OPTIMUM MEDIA UKRAINE, KYIV, UKRAINE.

Objective: . Aim: To evaluate the effectiveness of a multilevel rehabilitation program integrating physiotherapy (PT), transcranial electrical stimulation (TES), and endonasal breathing of a singlet-oxygen mixture (EBSO) on pain syndromes (PS), quality of life (QL), and levels of depression in professionals with type 2 diabetes mellitus (T2DM) and high psychophysical stress.

Patients And Methods: Materials and Methods: Sixty professionals with high psychophysical stress were randomly divided into three groups (n=20 each). Group 1 received standard rehabilitation. Group 2 underwent targeted PT, including ultrasound therapy for the pancreas projection and magneto-laser therapy for the liver projection and Th5-Th7 zones. Group 3 received the same PT as Group 2, supplemented with TES (alpha rhythm frequency) and EBSO. The rehabilitation program lasted two weeks, comprising 10 sessions. Outcomes were assessed using the QL questionnaire - SF-36 and Beck Depression Inventory-II (BDI-II).

Results: Results: Group 3 demonstrated significant improvements in QL by SF-36 score, particularly in Physical Functioning (from 49,2 ± 2,6 to 70,3 ± 3,8), Bodily Pain (from 48,1 ± 2,6 to 69,3 ± 3,1), and Mental Health (from 38,0 ± 3,3 to 59,3 ± 3,6; p < 0,01). Depression score decreased from 30,6 ± 2,1 to 18,2 ± 2,0 (p < 0,01), with notable improvements in cognitive-affective and somatic subscales. Group 2 showed moderate improvements, while Group 1 exhibited minimal changes.

Conclusion: Conclusions: Combining targeted PT with TES and EBSO significantly improves somatic and psychological outcomes in T2DM patients compared to standard rehabilitation or PT alone.