Objective: To explore the relationship between cancer-related fatigue (CRF) and locomotive syndrome (LS) among Chinese older adults with cancer.
Methods: This study was a cross-sectional survey. Staged random sampling method was employed to enroll 500 geriatric cancer patients from the Oncology Center of Jiangnan University Hospital in Wuxi, Jiangsu Province, China. Data were collected using General Information Questionnaire, Cancer Fatigue Scale and the Geriatric Locomotive Function Scale. χ2 test, Logistic regression analysis and Spearman analysis were utilized to analyze the data.
Results: A total of 466 geriatric cancer patients were enrolled in this survey. The occurrence of CRF was 43.8%, and the occurrence of LS was 30.9%. LS were risk factors for the occurrence of CRF in geriatric cancer patients. Advanced old age, fear of falling, comorbid with chronic diseases and CRF were risk factors for LS. CRF was positively associated with LS (r = 0.446, P < 0.001).
Conclusion: Our findings indicate a potential link between CRF and LS. By addressing LS from various aspects, including controlling the number of complications due to advanced old age and other factors, as well as spreading proper fall-related knowledge and controlling the awareness of fear of falling, healthcare professionals can indirectly alleviate CRF symptoms and improve the overall quality of life for these patients.
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0319511 | PLOS |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893112 | PMC |
Cancer Med
March 2025
Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
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Research Center for Clinical Medicine, Jinshan Hospital, Fudan University, Shanghai, China.
Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin-1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the serum level of FLOT1 in OC patients and found that the serum concentration of FLOT1 as well as CA125 was significantly increased in patients with OC compared with healthy control (p < 0.
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February 2025
Department of Geriatrics, Third Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China.
Gastric cancer (GC) is a prevalent malignant tumor that originates from the epithelial cells of the gastric mucosa, predominantly in the form of adenocarcinoma. Extensive research has confirmed the significant role of autophagy in the initiation, progression, and chemoresistance of GC. The potential of traditional Chinese medicine (TCM) to exert anti-tumor effects by modulating autophagy has been demonstrated, particularly in the context of GC prevention and treatment.
View Article and Find Full Text PDFUltrasound Med Biol
March 2025
Department of Ultrasound, Shenzhen Hospital of Southern Medical University, Shenzhen, China.
Parathyroid ultrasound is widely used in clinical practice and plays a crucial role in the diagnosis and treatment of parathyroid diseases. Nevertheless, ultrasound physicians frequently encounter a number of challenges and doubts in their professional practice. For this reason, Superficial Organs and Peripheral Vessels Committee of Chinese Association of Ultrasound in Medicine and Engineering has formulated the expert consensus on certain common clinical problems of parathyroid ultrasound based on the current research progress and clinical experience, in order to guide the clinical practice.
View Article and Find Full Text PDFPLoS One
March 2025
Department of Oncology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Objective: To explore the relationship between cancer-related fatigue (CRF) and locomotive syndrome (LS) among Chinese older adults with cancer.
Methods: This study was a cross-sectional survey. Staged random sampling method was employed to enroll 500 geriatric cancer patients from the Oncology Center of Jiangnan University Hospital in Wuxi, Jiangsu Province, China.
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