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Utility of CT perfusion in seizures and rhythmic and periodic patterns.
Clin Neurophysiol
December 2024
Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA; Epilepsy Center, Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA. Electronic address:
Objective: CT hyper-perfusion has been reported in non-convulsive status epilepticus (NCSE), while its occurrence and relevance after single seizures or with rhythmic and periodic patterns (RPPs) that lie along the ictal-interictal continuum (IIC), remain unclear. The goal of the study is to assess the role of CT perfusion (CTP) in diagnosing patients with clinical seizures, subclinical seizures, or RPPs that lie along the IIC, to help in the clinical assessment of these entities.
Methods: We retrospectively reviewed inpatients who underwent a CTP and an EEG within 6 h of each other.
Brain perfusion SPECT in the presurgical evaluation of epilepsy: is additional ictal SPECT required in case of high-confidence lateralization of the seizure onset zone by interictal SPECT and vice versa?
EJNMMI Res
September 2024
Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Background: Ictal brain perfusion SPECT provides higher sensitivity for the identification of the epileptic seizure onset zone (SOZ) than interictal SPECT. However, ictal SPECT is demanding due to the unpredictable waiting period for the next seizure to allow for ictal tracer injection. Thus, starting with an interictal scan and skipping the ictal scan if the interictal scan provides a SOZ candidate with high confidence could be an efficient approach.
View Article and Find Full Text PDFTwo different seizure networks on the scalp EEG present as ictal eye movements with epileptic nystagmus in a patient with cerebral hyperperfusion syndrome.
Seizure
October 2024
Ege University Faculty Of Medicine, Neurology Department, Izmir, Turkey.
Higher Validity, Lower Radiation: A New Ictal Single-Photon Emission Computed Tomography Framework.
Ann Neurol
December 2024
Department of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Objective: To assess whether arterial spin labeling perfusion images of healthy controls can enhance ictal single-photon emission computed tomography analysis and whether the acquisition of the interictal image can be omitted.
Methods: We developed 2 pipelines: The first uses ictal and interictal images and compares these to single-photon emission computed tomography and arterial spin labeling of healthy controls. The second pipeline uses only the ictal image and the analogous healthy controls.
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