Differences in escape respirator design can influence the wearer's ventilatory response and impact inspired oxygen (O) and carbon dioxide (CO) concentrations. There has been minimal investigation into the differences between hood and mask designs as escape respirators that compare between the ventilatory responses of wearing either a hood or mask escape respirator with an identical nose-cup. Thirty-nine healthy young males participated in the study. Each subject participated in two 20-min sessions of monitored breathing, wearing either a hood-type filtering facepiece respirator "CAPS 2000" (Shalon Chemical Industries, Israel & Supergum Industries Ltd, Israel) or an "Orange Diamond" filtering facepiece mask-type escape respirator (DEA Mop, Israel). Inspired gas concentrations of CO and O as well as the ventilatory response were recorded through a nose-cup during the test. Inspired CO, minute ventilation, breathing frequency, and the index of central ventilatory drive (V/T) were all significantly higher ( < 0.05) while wearing a mask respirator compared to a hood respirator. The hood respirator evaluated in the present study outperformed the mask respirator in most indices when measured at rest. The hood respirator had a reduced ventilatory demand compared to the mask respirator and may be advantageous for individuals with weaker respiratory systems, such as the elderly or those who suffer from respiratory diseases.
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http://dx.doi.org/10.1080/15459624.2025.2473463 | DOI Listing |
J Occup Environ Hyg
March 2025
Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel.
Differences in escape respirator design can influence the wearer's ventilatory response and impact inspired oxygen (O) and carbon dioxide (CO) concentrations. There has been minimal investigation into the differences between hood and mask designs as escape respirators that compare between the ventilatory responses of wearing either a hood or mask escape respirator with an identical nose-cup. Thirty-nine healthy young males participated in the study.
View Article and Find Full Text PDFRespir Res
May 2024
Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
The soft palate and back of the throat represent vulnerable early infection sites for SARS-CoV-2, influenza, streptococci, and many other pathogens. We demonstrate that snoring causes aerosolization of pharyngeal fluid that covers these surfaces, which previously has escaped detection because the inspired airstream carries the micron-sized droplets into the lung, inaccessible to traditional aerosol detectors. While many of these droplets will settle in the lower respiratory tract, a fraction of the respirable smallest droplets remains airborne and can be detected in exhaled breath.
View Article and Find Full Text PDFJ Environ Sci (China)
January 2024
Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, Guangzhou University, Guangzhou 510006, China.
Increasing risks of incidental and occupational exposures to two-dimensional transition metal dichalcogenides (2D TMDCs) due to their broad application in various areas raised their public health concerns. While the composition-dependent cytotoxicity of 2D TMDCs has been well-recognized, how the outer chalcogenide atoms and inner transition metal atoms differentially contribute to their perturbation on cell homeostasis at non-lethal doses remains to be identified. In the present work, we compared the autophagy induction and related mechanisms in response to WS, NbS, WSe and NbSe nanosheets exposures in MH-S murine alveolar macrophages.
View Article and Find Full Text PDFFront Immunol
August 2022
Department of Medicine, Duke University Health System, Durham, NC, United States.
Occupational exposure to inhaled crystalline silica dust (cSiO2) is linked to systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, and anti-neutrophil cytoplasmic autoantibody vasculitis. Each disease has a characteristic autoantibody profile used in diagnosis and implicated in pathogenesis. A role for cSiO2 in modulating humoral autoimmunity is supported by findings in mice, where respirable cSiO2 induces ectopic lymphoid structures as well as inflammation in exposed lungs across genetically diverse backgrounds.
View Article and Find Full Text PDFPediatr Pulmonol
September 2022
Division of Neonatology, Paracelsus Medical University, Salzburg, Austria.
Objective: Invasive mechanical ventilation poses a strong risk factor for the development of chronic lung disease in preterm infants. A reduction of the dead space as part of the total breathing volume would reduce the ventilation effort and thereby lower the risk of ventilator-induced lung injuries. In this experimental study, we compared the efficacy of mechanical dead space washout via uncontrolled and controlled leakage flow in their ability to eliminate CO during conventional ventilation in preterm infants.
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