Introduction: Tramadol abuse is a current public health concern in Ethiopia. Drug abuse including that of tramadol is a significant public health issue that causes health, economic, and social problems to individual drug users, their families, the community, and the entire nation. Therefore this study delivers information regarding current tramadol abuse among students of an Ethiopian University.
Objective: The aim of this study is to assess the prevalence of tramadol abuse and associated factors among Hawassa university students, February to June 2023.
Methods And Materials: A cross-sectional study was performed among 402 randomly selected Hawassa university students. Data was collected from participant through self-administered researcher made questionnaire using kobo toolbox software applications. Data from kobo toolbox were directly exported to and analyzed by using SPSS version 26 software. Binary logistic regression was applied to identify the factors associated with tramadol abuse. In the final model, Adjusted Odds Ratio, and 95% CI was used to measure the strength of association and P-value less than 0.05 considered statistically significant.
Result: A total of 402 students were enrolled in this study of which 46 students (11.4%) [95% CI 8.5-14.7] had history of tramadol abuse once in their lifetime with 23.9% of them were active tramadol abuser with some dependence behaviors. The result of multivariate analysis shows that having a friend who use drugs [AOR = 1.691, 95% CI (0.718-3.980), p = 0.041], knowing about tramadol [AOR = 13.766, 95%CI (3.003-63.113), p = 0.001] and having the history of taking tramadol with physicians prescription in their life time [AOR = 7.960, 95%CI (3.603-17.587), P < 0.001] were the significant predictors of tramadol abuse.
Conclusion: The life time prevalence of tramadol abuse among university students is high and it demands attention of government and the general public.
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0318634 | PLOS |
PLoS One
March 2025
Department of Anesthesia, Faculty of Medicine, College of medicine and health science, Hawassa University, Hawassa, Sidama, Ethiopia.
Introduction: Tramadol abuse is a current public health concern in Ethiopia. Drug abuse including that of tramadol is a significant public health issue that causes health, economic, and social problems to individual drug users, their families, the community, and the entire nation. Therefore this study delivers information regarding current tramadol abuse among students of an Ethiopian University.
View Article and Find Full Text PDFPLoS One
March 2025
Discipline of Pharmaceutical Sciences, School of Health Sciences, Westville Campus, University of KwaZulu-Natal, Durban, South Africa.
Introduction: There is an ongoing global upsurge of opioid misuse, fatal overdose and other related disorders, significantly affecting the African continent, due to resource-limited settings and poor epidemiological surveillance systems. This scoping review maps scientific evidence on epidemiological data on unlawful opioid use to identify knowledge gaps and policy shortcomings.
Method: The databases (PubMed, Scopus, Web of Sciences) and references were searched guided by Population, Concept, and Context (PCC) and PRISMA-ScR.
Sci Total Environ
February 2025
Analytical Chemistry Department, Universitat de València, Dr. Moliner 50, 46100 Burjassot, Spain. Electronic address:
Monitoring the presence of illicit and pharmaceutical drugs in wastewater has emerged as a powerful tool for determining drug consumption patterns and trends within a specific population group. In this study, an analytical method has been developed to determine the presence of forty psychoactive substances, including stimulants, benzodiazepines, antidepressants, and opioids, in wastewater. The proposed approach combines in-situ wastewater single sampling, solid-phase extraction, and ultra-high performance liquid chromatography coupled with tandem mass spectrometry determination.
View Article and Find Full Text PDFJ Psychoactive Drugs
February 2025
Aging and Development Unit, African Population and Health Research Center, Nairobi, Kenya.
The world is witnessing a pharmaceutical opioid crisis, and in Africa's version, the nonmedical use of Tramadol is prevalent in vulnerable populations. However, data on the factors promoting nonmedical use of Tramadol in slums is generally lacking. The study explored the factors that promote the nonmedical use of Tramadol among urban slum-dwelling youth in the Asokore Mampong Municipality, Ghana.
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