Artificial intelligence (AI) is transforming healthcare by enhancing clinical decision-making, particularly in nursing, where it supports tasks such as diagnostics, risk assessments, and care planning. However, the integration of non-explainable AI (NXAI) - which operates without fully transparent, interpretable mechanisms - presents ethical challenges related to accountability, autonomy, and trust. While explainable AI (XAI) aligns well with nursing's bioethical principles by fostering transparency and patient trust, NXAI's complexity offers distinct advantages in predictive accuracy and efficiency. This article explores the ethical tensions between XAI and NXAI in nursing, advocating a balanced approach that emphasises outcome validation, shared accountability, and clear communication with patients. By focusing on patient-centred, ethically sound frameworks, it is argued that nurses can integrate NXAI into practice, addressing challenges and preserving core nursing values in a rapidly evolving digital landscape.
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http://dx.doi.org/10.12968/bjon.2024.0394 | DOI Listing |
J Exp Anal Behav
March 2025
Behavioral Neuroscience Laboratory, Department of Psychology, Boğaziçi University, Istanbul, Turkey.
Robots are increasingly used alongside Skinner boxes to train animals in operant conditioning tasks. Similarly, animals are being employed in artificial intelligence research to train various algorithms. However, both types of experiments rely on unidirectional learning, where one partner-the animal or the robot-acts as the teacher and the other as the student.
View Article and Find Full Text PDFAdv Healthc Mater
March 2025
Department of Hepatobiliary and Pancreatic Surgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China.
Pyroptosis, a form of programmed cell death mediated by the gasdermin family, has emerged as a promising strategy for inducing anti-tumor immunity. However, efficiently inducing pyroptosis in tumor cells remains a significant challenge due to the limited activation of key mediators like caspases in tumor tissues. Herein, a self-priming pyroptosis-inducing agent (MnNZ@OMV) is developed by integrating outer membrane vesicles (OMVs) with manganese dioxide nanozymes (MnNZ) to trigger pyroptosis in tumor cells.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
March 2025
Southeast University, School of Chemistry and Chemical Engineering, Moling Street, Jiangning District, 211189, Nanjing, CHINA.
Co-crystal engineering is of interest for many applications in pharmaceutical, chemistry and material fields, but rational design of co-crystals is still challenging. Although artificial intelligence has brought major changes in the decision-making process for materials design, yet limitations in generalization and mechanistic understanding remain. Herein, we sought to improve prediction of co-crystal by combining mechanistic thermodynamic modeling with machine learning.
View Article and Find Full Text PDFAm J Respir Crit Care Med
March 2025
University of Iowa, Radiology and Biomedical Engineering, Iowa City, Iowa, United States;
Rationale: Quantifying functional small airways disease (fSAD) requires additional expiratory computed tomography (CT) scan, limiting clinical applicability. Artificial intelligence (AI) could enable fSAD quantification from chest CT scan at total lung capacity (TLC) alone (fSAD).
Objectives: To evaluate an AI model for estimating fSAD, compare it with dual-volume parametric response mapping fSAD (fSAD), and assess its clinical associations and repeatability in chronic obstructive pulmonary disease (COPD).
Radiol Artif Intell
March 2025
Department of Radiology & Biomedical Imaging, University of California, San Francisco (UCSF), San Francisco, Calif.
Retrieval-augmented generation (RAG) is a strategy to improve performance of large language models (LLMs) by providing the LLM with an updated corpus of knowledge that can be used for answer generation in real-time. RAG may improve LLM performance and clinical applicability in radiology by providing citable, up-to-date information without requiring model fine-tuning. In this retrospective study, a radiology-specific RAG was developed using a vector database of 3,689 articles published from January 1999 to December 2023.
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